Question

< Question 10 of 18 > “To calculate AG for an ion, you simply add the equations for the chemical and electrostatic components together. AG = RT IN (6) +ZFV. Say you are trying to move Ca²+ into a frog muscle cell through its ionotropic Ach receptors after they are stimulated by the neurotransmitter. For a typical frog muscle cell, the concentration of Ca²+ is 0.100 mM inside the cell and 2.10 mM outside the cell. As mentioned earlier, a typical animal cell resting membrane potential is –60 mV, and this process occurs at body temperature, which is 310 K.” Given these parameters, what is the AG for Ca2+ ion transport into the frog muscle cell in the presence of Ach? AG = kJ/mol

Answer 1

∆G = 2.303 RTLog (ca2+ in/ ca2+ out)+ nExF

∆G= 2.303 x8.314x310xlog(0.1/2.1)+2x-60x10^-3x96500

∆G=5935.61x-1.3- 11580= -7716.35-11580= -19296= -19.3kj/mol

Hope it's clear..thanks