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and few mitochondH O D Fast fibers that have high levels of myoglobin and many mitochondria. QUESTION 20 12 points Save Ans Malignant hyperthermia is a rare condition stimulated by certain anesthetics. The individuals muscles suddenly become rigid and body temperature increases rapidly Individuals that are at risk for malignant hyperthermia have a mutation that results in excessive opening of the Ca2 channels in the sarcoplasmic reticulum. Based on this information answer the following questions. 1) Explain how excessive release of Ca2 results in increased muscle tension. 2) Explain how excessive Ca release increases body t 3) How is Ca+ removed from the sarcoplasm? T TT Arial Click Save and Submit to save and submit. Click Save All Answers to save all answers. Save All Answers Save a
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Malignant hyperthermia is a rare condition stimulated by certain anesthetics. The Individuals that are at risk for malignant hyperthermia have a mutation that results in excessive opening of the Ca2 channels in the sarcoplasmic reticulum. Based on this information answer the following questions individuals muscles suddenly become rigid and body temperature increases rapidly 1) Explain how excessive release of Ca2 results in increased muscle tension The membrane activation (of the muscle fiber) triggers the release of calcium (Ca1-) from the sarcoplasmic reticulum. These calcium ions bind to the troponin in the muscle filament, which causes the exposure of myosin binding sites on actin. The actin-myosin cross bridge forms and muscle contraction occursody 2) Explain how excessive Ca release increases body temperature. Excessive calcium increase the muscle contraction, which increase the metabolic rate, and generate more heat. This results in increased body temperature 3) How is Ca removed from the sarcoplasm? Calcium is pumped back through an ative transport pump. ATP is needed to power the calcium transport pump that pumps calcium from the sarcoplasm back into the sarcoplasmic reticulum.

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