In order to predict the products in an organic reaction scheme, one must understand the role of the reagents involved in the reaction.
In the first step, LDA is used in the presence of THF. Here, LDA is used as a base, which means it'll draw out a proton from the ketone reactant, leaving behind an enolate form which would then interact with CH3I in the second step.
In the second step enolate form of the reactant would act as a nucleophile and the carbon in CH3I would act as an electrophile, also, I- is a good leaving group.
The interaction and the reaction mechanism with the expected product are in the image given below:
Please draw the product/s for this base catalyzed reaction 1. LDA, THE 2. CH31
2) Draw the major product for the base-catalyzed reaction below. ОН
HW 5 1. Draw all possible products for the base catalyzed reaction of ethanal and propanal. Indicate the new bond formed. (Full: all possible products and correct ID of new bond, partial: 75% of possible products) 2. Draw and label the kinetic and thermodynamic products for reacting the following ketone with LDA. (Full: correct products and labeling, partial: correct products but no labels) 1. LDA 2 CH31 3. Show the mechanism for the following intramolecular reaction. You do NOT need...
1) Predict the major product for the following reaction. (LDA is a strong base) 1. LDA H 2. نم H LDA 3. H20
Provide the major organic product of the following reaction. 1. LDA 2. CHAI Draw the molecule on the canvas by choosing buttons from the Tools (for bonds), Atoms, * H 120 EXP CONT H С + N S NN CI Br
Draw the mechanism and the product(s)for the acid-catalyzed reaction of (S)-4-chloro 2-pentanone with 2 moles of methanol; indicate which is the hemiacetal and the acetal structures. Consider how would the mechanism and the product be different if the same ketone underwent acid hydrolysis in the absence of methanol? Also, consider the reversibility of the above mechanisms.
1) Draw the major product of the following intramolecular reaction. 2) Draw the major product of the following reaction that begins with a retro-aldol, followed by an intramolecular aldol condensation. 3) Determine and draw the structures of compounds A and B only. Do not draw the structure of compound X. Place each structure above its letter. HINT: Both A and B are esters. 4) Draw a curved arrow mechanism for the following acid-catalyzed isomerization reaction. You must show all intermediates....
Draw the major organic product of the reaction shown below. 1. LDA, THF on 2. CH,I, HMPA 3. H', H,
Draw the product of the following reaction sequence. Ho, 6 ܂ 1.LDA,THF
Draw the coupling product for the Pd(0) catalyzed Suzuki reaction Draw the coupling product of the Pd(0)-catalyzed Suzuki reaction between the following compounds. Show the stereochemistry of the product.
please help 2. 3 pts) Lithium disopropyl amide (LDA) could theoretically act as a nucleophile or a base. With that in mind, draw the four theoretical products (3 from E2 and 1 from S,2) of the reaction below. Then, circle the major product. Provide a brief rationale. Br