Question

Complete each sentence to assess your knowledge of neurotransmitter storage and release at a typical neuronal synapse.

Complete each sentence to assess your knowledge of neurotransmitter storage and release at a typical neuronal synapse, SNARE As action potentials propagate along a myelinated fiber, they jump from one node of Ranvier to the next and for this reason such propagation is called reuptake presynaptic Eventually, the action potential reaches the terminal of the neuron postsynaptic Depolarization in the terminat induces the opening of synaptic cleft saltatory conduction The electrochemical gradient for terminal favors the flux of this ion the axon synaptotagmins that are Ca entering during depolarization binds to a family of proteins known as associated with located within the axon terminal. enzymes ionotropic This binding triggers a conformational change in the fusion and the release of complex that leads to membrane vesicles diffusion Neurotransmitters diffuse across the and bind to receptors within the membrane of the neuron that are ion channels, which designates them as receptors into Altematively, activated receptors may act indirectly on separate ion channels through a G protein and/or second messenger, a type referred to as receptors. neurotransmitters vollage-gated Ca channels Finally, neurotransmitters are removed from the synaptic cleft by into the presynaptic axon terminal, by away from the receptor site, or by destruction by ca metabotropic

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Answer 1

Answers in order.

1. Saltatory conduction.

2. Presynaptic.

3. voltage-gated Ca²⁺ channels.

4. Ca²⁺, into.

5. synaptotagmins, vesicles.

6. SNARE, neurotransmitters.

7. synaptic cleft, postsynaptic, ionotropic.

8. metabotropic.

9. reuptake, diffusion, enzymes

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