Question

Opgave 3. The main molecule in this exercise is B-D-2'-deoxythymidine (thymidine), see Figure 1.1. Figur 1.1. The chemical structure of thymidine and numbering of atoms. Note that atoms in the sugar moiety are labelled with primes (e.g. CI' and HI') while atoms in the nucleobase are label led without primes (e.g. C6 and H6). NH H6-6 C2 .Nr/ >O H5'a H3' H2 он H2'b a+b) 'H, 13c, COSY, 'H,13C-HSQC, DEPT and NOE-difference spectra of thymidine recorded in D2O are shown in Figures 1.3, 1.4 og 1.5. Assign the 1 H and 13 C resonances in thymidins. Signals are located at: H-NMR: 8 (in ppm) 1,9; 2,3; 3,8; 4,0; 4,4; 6,3; 7.6 1C-NMR: 8 (in ppm) 15; 40; 63; 72; 87;89; 113; 140; 152; 168

Answer 1