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A new disease, MSC-2020, has just emerged in the southeast corner of Michigan. Initial studies indicate...

A new disease, MSC-2020, has just emerged in the southeast corner of Michigan. Initial studies indicate that it is caused by a double stranded DNA virus whose genome produces 4 large polypeptides that code for 11 different proteins, including a predicted viral spike protein that shows affinity for a protein called EMA that is on the surface of epithelial cells. Based on this information, how might you start designing an antiviral drug to fight MSC-2020? Give at least two different targets or approaches and why they make sense.

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Answer #1

If someone used EMA antibody (soluble)this will bind the ema and thus viral spike protein will not be able to bind and thus they will not be able to infect the new epithelial cells.

The. Other mechanism can be translation inhibitor that will specifically inhibit the protein synthesis of virus but it will also affect the host cells protein synthesis BECAUSE viral DNA translate with host translation.

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