Question

+H2N +H20 The reaction is, to some extent, reversible and so in competition experiments there can be a difference between product mixtures assessed immediately and those that are analysed after having been left for a long period of time (i)Give the mechanism of formation of the semicarbazone from cyclohexanone (ii)In the following mixture (shown below), which compound would react fastest with semicarbazide to make the semicarbazone? Explain your answer Which compound would react more slowly, but would be present in greatest amount after a period that is long enough to establish an equilibrium (reflecting it being the more stable product)? Explain your answer (iii) In your answer use structures of the intermediates involved and concepts that might include: location of the charge; loss of aromaticity; activation/deactivation of the ring; resonance; electronegativity; nucleophilicity; bond strength; chirality; molecular weight; solubility; cost; toxicity; colour; crystallinity; melting point; etc

Answer 1

NM 2 NM NH ane more Vealhus.. eYi decreased