If you change the structure of a small molecule, and the ∆G° of protonation of the molecule changes by -2.94 kcal/mol, what happens to the pKa?
If you change the structure of a small molecule, and the ∆G° of protonation of the...
5. How does protonation change the structure of carbonate? (adding an H+to CO32- ) 6. Sulfur dioxide and carbon dioxide have somewhat different properties, in spite of the fact that both are triatomic molecules with two terminal oxygen atoms. Can you explain why they are as different as they are? 7. Because carbon tetrachloride is not soluble in water, a test tube containing the two liquids will form two layers. Predict which layer is on top and justify your answer....
1. Use your own words or drawing to show the protonation and deprotonation of Lysine when PH increase from 1 to 11. 2. We know that the pKa of Histidine is 6.5. Explain what will happen at physiological pH. And it is the residue most frequently involved in enzymemediated catalysis. Explain why base on the known features of Histidine. You can use serine protease Trypsin as an example. These are my protein structure homework, pls help
Orange G and Blue dextran are in the mixture. Orange G is a small molecule, whereas blue dextran is relatively big. Which one flows out first? Which one flows out later? Why? 2. You need to purify a protein that is enriched with glutamate (i.e. acidic protein). What kind of chromatography would you use? 3. EGF (epidermal growth factor) is highly associated with malignant breast cancer. You have generated an antibody against EGF to screen the breast tissues. However, there...
For the following molecule (Bronsted Acid) answer the questions. HOCH2CH2CCCH2CH2C(O)OH 6. Draw the structure in perspective representation. 7. Show the valence electron count. 8. What are the functional group(s) in the molecule? Spelling counts. 9. What is the pKa of the functional groups on the pKa list. 10. What is the hybridization of the bolded atoms? 11. Show the hybrid orbital diagram of the bolded atom?
The standard enthalpy change for the following reaction is -415 kJ at 298 K. Zn(s) + Ch(g) → ZnCl2() AH° = -415 kJ What is the standard enthalpy change for the reaction at 298 K? ZnCl(s) — Zn(s) + Cl2(g) The standard enthalpy change for the following reaction is -50.6 kJ at 298 K. N2H40 - N2(g) + 2 H2(g) AH° = -50.6 kJ What is the standard enthalpy change for this reaction at 298 K? N2(g) + 2 H2(g)...
Change the bond between the two carbon atoms in each molecule to a double or triple bond as needed to complete the structure. If the bond should remain a single bond, then you do not need to do anything to the bond. Do not change any other bonds in the molecules.
STRUCTURE WILL VARY DEPENDING IF PKA IS LARGE OR SMALL, Draw a formula for Val-Ser-Gly (V-S-G) in its predominant ionic form at pH 7.3. You may assume for the purposes of this question that the pKa values of the acidic groups of amino acid residues in the peptide are the same as in the amino acid itself. You do not have to consider stereochemistry. You do not have to explicitly draw H atoms. Do not include lone pairs in your...
Which molecule is hydrolyzed by myosin to provide the energy for a conformational change in the myosin structure in muscle contraction? A. ADP B. ATP C. AMP D. Pi
1. Identify the most acidic proton in each molecule. Briefly explain your reasoning based on structure (stating the pKa value is not enough, here. You must bring in factors related to ARIO). OH HACO NO2
what changes occur in the structure of a protein molecule when it becomes denatured