Aspartate transaminase catalyzes the following reaction: Aspartate + α-ketoglutarate ↔ oxaloacetate + glutamate. It has a cofactor called PLP and the deltaG of Aspartate transaminase to PLP is -8.2 kJ/mol under nominal biological conditions. 1. What is the Keq 2. If the deltaG is -6 kJ/mol how is Keq changed?
Aspartate transaminase catalyzes the following reaction: Aspartate + α-ketoglutarate ↔ oxaloacetate + glutamate. It has a...
Write the mechanism of the PLP-dependent transamination reaction of glutamate and oxaloacetate to yicld α-ketoglutarate plus aspartate. 5.3
The enzyme hexokinase catalyzes the following reaction: Glucose + ATP ↔ Glucose 6-phosphate + ADP For this reaction, ΔG° = +16.7 kJ/mol a. Calculate the equilibrium constant for this reaction at 25 °C. Is this reaction spontaneous under standard conditions at this temperature? Calculate the ΔG if the reaction temperature was 25 °C and the concentrations are: glucose, 55.0 mM,; ATP, 5.00 mM; ADP, 1.00 mM; and glucose 6-Phosphate, 0.100 mM. Would the reaction be spontaneous under the conditions of...
1. A chemical reaction "A" has a DG of -10 kcal/mole. Calculate the key for the reaction A. Show the equation that you have used and all the calculations to get full credit. (2 pts). 2. State two common features among most of the activate carriers that you have studied in class. (2 points) 3. Study the sequence of the peptide given below and answer the following questions based on the peptide sequence given below. AGLRHTICHMKDCFY (10 points) A. Name...