Question

Which of the following statement associated with your endodermal research papers is NOT correct? Select one:

Select one:

a. Long-term loss of Cdx2 led to a partial conversion of the intestinal epithelium to a stomach-like nature.

b. Pdx1 is not involved in pancreatic bud specification.

c. Foxa1 and Foxa2 are required for uptegulating Pdx1 expression in the pancreatic buds.

d. Foxa proteins are required to make the endoderm competent to respond to FGF and form liver.

e. Upregulation of Sox2 in the foregut leads to an inability to separate into the trachea and esophagus.

Answer 1

d. Foxa proteins are required to make the endoderm competent to respond to FGF and form liver is incorrect according to endodermal research papers.

Foxa 1 and Foxa 2 are essential for hepatic specification. Foxa proteins function as pioneer proteins to open compacted chromatin in regulatory regions of liver specific genes.