Would the following compound be expected to undergo a rapid E2 elimination when treated with NaOMe?...
34. Which of the following molecules will readily undergo an elimination reaction when treated with NaOCH3? . d. 1 BO
Which of the following alkyl bromides would undergo a relatively fast E2-type elimination reaction? Br Br A) B) C) D) Br odov Br A B D
Which of the following alkyl bromides would undergo a relatively fast E2-type elimination reaction? Br Br A) B) C) D) oc "A dd Br Br А с
2. Isomers A and B undergo dehydrohalogenation when treated with sodium methoxide (NaOme); however, one isomer reacts > 1000 times faster than the other. Identify the more reactive isomer and justify your answer using chair structures (1 pt).
3. Explain why molecule A readily undergoes E2 elimination whole molecule B does not undergo E2 elimination: (trans-decalin for both) (Draw the chair forms of A and B and show whether an anti- or synperiplanar conformation is possible. Models are VERY useful here.)
(2 points) When the alcohol below is treated with and pyridine, the expected elimination product is formed. However, when the same alcohol is treated with, the elimination product is 1,2-dimethylcyclopentene. Propose a mechanism for each pathway to account for these differences 1. POC3 pyridine OH SO4 2. Predict the mechanism for the following conversion (2 points) Hgo
draw the products that are expected when the following compound is treated with a Grubbs catalyst. If several products or isomers are possible, draw all structures. Got this one wrong, please help. Your answer is incorrect. Try again. Draw the products that are expected when the following compound is treated with a Grubbs catalyst. If several products or isomers are possible, draw all struct CH Edit HC LINK TO TEXT
6. Predict which of the following two isomers (cis- or trans-) will undergo an E2 elimination under the treatment with EtoNa in EtOH more rapidly. A) For the explanation of the reaction rate, draw chair conformations for each isomer, determine which conformation is more stable . B) Draw the major product and the mechanism of the reactions. CI cis-isomer trans-isomer
Why does triphenylmethane fail to undergo a reaction when treated with an acid or base (mention the pKa of the neutral compound triphenylmethane and acid/base equilibrium)?
Chem 2200 E1/E2 Practice Problems tn 1. Predict the major produc t in each of the following reactions Ha OEt b) Br Ph 2. When 1-chloro-oox(Compound I) is treated with sodium methoxide in methanol, elimination readily occurs to give 1,2-x0oxd compound I). However, the two diastereomers of i (la and lb) each give one single isomer of il (either lla or lib) as shown below. Provide structures for la and ib as well as a mechanistic explanation for the stereopecificity....