Question

2) Organize the following substituted acetophenones by increasing acidity of the alpha‐proton. Consider the stabilization or destabilization of the enolate (conjugate base) when determining relative acidities.

لي بن ast acidic) _ (most acidic)

Answer 1

For its solution we need to know +m effect and - m effect.

+m effect when atom gives its lone pair or e- to benzene ring is called +m effects.

-m effect : whenb atom withdraw e- from benzene ring to itself is callwd - m.

So if No2 has higher power for withdrawal of e-. So it can give - m. i hope u understand the solution

Feffect 0:0 3.50 в го o chz LESS! LESS ACIDIC ТЧ Grave tM so Too'MUCH STABLE фHI ALY ACIDIC ТИА АЛ) NO2 NOT AeISго ko IT WILL WORK AS BAJ B ea ALB A

Plzz hit a like

Thanks