Question

“My husband was diagnosed with X-linked recessive spondyloepiphyseal dysplasia tarda, an inherited skeletal disorder with physical characteristics that include moderate short-stature (dwarfism); moderate to severe spinal deformities; barrel-chest; disproportionately short trunk and neck; disproportionately long arms, and premature osteoarthritis, especially in the hip joints. Final male adult height ranges from 4 feet 10 inches to 5 feet 6 inches. There are no other examples of this in either of our immediate families.” What are the chances that my future daughter(s) will be carriers for this condition?

Answer 1

In a total offspring the chance of female carrier is 1/2.

The probability of female carriers in the total females from the above cross is 1. Becuse all females from the above cross carry a recessieve allele.

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