Question

5. A sickly blue-eyed person who has both sickle cell anemia and cystic fibrosis meets another person who is known to carry the genes for SCA, CF, and blue eyes. In what phenotypic ratio might their potential childrens eyes appear? Phenotypes of childrens eye colors with ratios
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Answer #1

Blue eyes in humans is recessive to brown eyes.
SCA WT allele = S
SCA mutant allele = s
CF WT allele = C
CF mutant allele = c
Eye color WT allele = B
Eye color mutant allele = b

Person 1 = ssccbb
Person 2 = SsCcBb
Parental cross: ssccbb X SsCcBb
Gametes: (scb) X SCB SCb Scb ScB sCB sCb scb scB
Progeny: SCB/scb SCb/scb Scb/scb ScB/scb sCB/scb sCb/scb scb/scb scB/scb

Half the progeny will have blue eyes.

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