Question

Response 42) This signal molecule is produced by endothelial cells that line blood vessels, freely diffuses a short distance into neighboring cells, and leads to localized vasodilation (increased blood flow). a) Calcium b) Nitric oxide c) Calmodulin d) Aldosterone

Answer 1

Nitric oxide is produced by endothelial cell that line blood vessels. It increase intracellular cyclic GMP and causes vasodilattation.

It bind heme moeity of cytosolic guanylate cyclase and activate guanylate cyclase and increase intracellular cyclic GMP.and thus causes vasodilattation