Question

If the equilibrium constant for the acid dissociation is KA and pKA (-log Ka) =7.0, what...

If the equilibrium constant for the acid dissociation is KA and pKA (-log Ka) =7.0, what is the ratio of [HPO42-] to [H2PO4−] in this buffer system? Please show your calculation.

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Answer #1

The molar ratio is calculated using the Henry Hasselbach equation:

[HPO4-2] / [H2PO4-2] = 10 ^ (pH - pKa) = 10 ^ (7 - 7.2) = 0.63

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