Chymotrypsin What evidence in chymotrypsin mechanism supports the claim that chymotrypsin catalysis involves general acid-base catalysis...
- Chymotrypsin
- What evidence in chymotrypsin mechanism supports the claim that chymotrypsin catalysis involves general acid-base catalysis and covalent catalysis?
- Draw the chemical structure of the transition state (resembles the intermediate structure) in the step that forms the enzyme-product covalent adduct.
- In comparison to the substrate, how is the tetrahedral transition state preferentially stabilized by enzyme?
- Chymotrypsin mechanism: Write all the steps in the mechanism and understand what each step accomplishes.
Homework Answers
Add Answer to:
Chymotrypsin
What evidence in chymotrypsin mechanism supports the claim that
chymotrypsin catalysis involves general acid-base catalysis...
Put these steps in the mechanism of chymotrypsin catalysis in order from first to last. Note...
Put these steps in the mechanism of chymotrypsin catalysis in order from first to last. Note that some references may not break out each of these steps individually, but all steps should be ordered. There will be eight steps. First step His 57 catalyzes removal of H from Ser 195 hydroxyl. Ser 195's nucleophilic O attacks carbonyl C of substrate. The portion (the C-terminal end) of original substrate with the new amino terminus diffuses away. His 57 donates H to...
Put these steps in the mechanism of chymotrypsin catalysis in order from first to last. Note...
Put these steps in the mechanism of chymotrypsin catalysis in
order from first to last. Note that your textbook may not break out
each of these steps individually, but all steps should be ordered.
(There will be eight steps.
)
first step last step Resulting OH attacks carbonyl of remaining substrate. His 57 donates H to Ser 195 O, leading to collapse of tetrahedral intermediate. mato Ser 195 the portion (N-terminal end) of original substrate with the new carboxylate terminus...
Based on the document below, 1. Describe the hypothesis Chaudhuri et al ids attempting to evaluate;...
Based on the document below,
1. Describe the hypothesis Chaudhuri et al ids attempting to
evaluate; in other words, what is the goal of this paper? Why is he
writing it?
2. Does the data presented in the paper support the hypothesis
stated in the introduction? Explain.
3.According to Chaudhuri, what is the potential role of thew
alkaline phosphatase in the cleanup of industrial waste.
CHAUDHURI et al: KINETIC BEHAVIOUR OF CALF INTESTINAL ALP WITH PNPP 8.5, 9, 9.5, 10,...
What are the instruments that have been utilized for the review article discussions? ` 1. Introduction...
What are the instruments that have been utilized for the
review article discussions?
`
1. Introduction In recent years, nanoclays have been the object of particular interest for many scientists and researchers in chemistry, physics, engineering and biology due to their excellent properties as well as their sustain- ability [1-3]. For instance, they represent the starting point to the de velopment of smart materials for drug delivery (4-9), food packaging [10-12), environmental remediation and wastewater treatment [13], cultural heritage [14–17and...
1. According to the paper, what does lactate dehydrogenase (LDH) do and what does it allow...
1. According to the paper, what does lactate dehydrogenase
(LDH) do and what does it allow to happen within the myofiber? (5
points)
2. According to the paper, what is the major disadvantage of
relying on glycolysis during high-intensity exercise? (5
points)
3. Using Figure 1 in the paper, briefly describe the different
sources of ATP production at 50% versus 90% AND explain whether you
believe this depiction of ATP production applies to a Type IIX
myofiber in a human....
Put these steps in the mechanism of chymotrypsin catalysis in order from first to last. Note that some references may not break out each of these steps individually, but all steps should be ordered. There will be eight steps. First step His 57 catalyzes removal of H from Ser 195 hydroxyl. Ser 195's nucleophilic O attacks carbonyl C of substrate. The portion (the C-terminal end) of original substrate with the new amino terminus diffuses away. His 57 donates H to...
Put these steps in the mechanism of chymotrypsin catalysis in
order from first to last. Note that your textbook may not break out
each of these steps individually, but all steps should be ordered.
(There will be eight steps.
)
first step last step Resulting OH attacks carbonyl of remaining substrate. His 57 donates H to Ser 195 O, leading to collapse of tetrahedral intermediate. mato Ser 195 the portion (N-terminal end) of original substrate with the new carboxylate terminus...
Based on the document below,
1. Describe the hypothesis Chaudhuri et al ids attempting to
evaluate; in other words, what is the goal of this paper? Why is he
writing it?
2. Does the data presented in the paper support the hypothesis
stated in the introduction? Explain.
3.According to Chaudhuri, what is the potential role of thew
alkaline phosphatase in the cleanup of industrial waste.
CHAUDHURI et al: KINETIC BEHAVIOUR OF CALF INTESTINAL ALP WITH PNPP 8.5, 9, 9.5, 10,...
What are the instruments that have been utilized for the
review article discussions?
`
1. Introduction In recent years, nanoclays have been the object of particular interest for many scientists and researchers in chemistry, physics, engineering and biology due to their excellent properties as well as their sustain- ability [1-3]. For instance, they represent the starting point to the de velopment of smart materials for drug delivery (4-9), food packaging [10-12), environmental remediation and wastewater treatment [13], cultural heritage [14–17and...
1. According to the paper, what does lactate dehydrogenase
(LDH) do and what does it allow to happen within the myofiber? (5
points)
2. According to the paper, what is the major disadvantage of
relying on glycolysis during high-intensity exercise? (5
points)
3. Using Figure 1 in the paper, briefly describe the different
sources of ATP production at 50% versus 90% AND explain whether you
believe this depiction of ATP production applies to a Type IIX
myofiber in a human....
Most questions answered within 3 hours.
-
Assume Kw = 1.01 ✕ 10−14
For pure water, we can calculate [H3O+ ] = [OH...
asked 23 minutes ago -
Suppose that on a temperature scale X, water boils at 203.0°X
and freezes at -105.7°X. What...
asked 1 hour ago -
BaS crystallizes in a cubic unit cell with S2- ions on each
corner and each face....
asked 1 hour ago -
A. 0≤P(Oi)≤10≤P(Oi)≤1 for each i
B. P(Oi)≤0P(Oi)≤0
C. P(Oi)=1+P(OCi)P(Oi)=1+P(OiC)
D. P(Oi)≥1P(Oi)≥1
If an experiment consists of...
asked 3 hours ago -
A battery has an emf of 9.20V and an internal resistance of 1.20
ohm. a)What resistance...
asked 3 hours ago -
The area of an elastic circular loop decreases at a constant
rate, dA/dt = −6.60×10−3 m2/s...
asked 4 hours ago -
The denaturation of proteins can be described by the
equilibrium
F⇌U
where F and U represent...
asked 5 hours ago -
Please answer what the maximum and minimum force is, and the
angle on the ion is...
asked 5 hours ago -
implement a program that reads a number of rows and a symbol.
The program will draw...
asked 6 hours ago -
Assume that when adults with smartphones are randomly selected,
45% use them in meetings or classes....
asked 6 hours ago -
Determine the number of formula units of
Na2SO4 and moles of oxygen contained in 8.11
moles...
asked 6 hours ago -
Explain in steps on the following code
What would be the output when executed
using System;...
asked 6 hours ago