Question

After determining that both y and e are recessive mutations, you decide to determine if these...

After determining that both y and e are recessive mutations, you decide to determine if these genes interact, since they both affect melanin accumulation but in opposite ways. To do this you make the following cross:

y/y, E/E   (yellow ♀) X    Y/Y, e/e    (ebony ♂)

Show the genotypes which would segregate in the F1 and F2 generations with their expected ratios. Assume the two genes are unlinked and segregate independently

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Answer #1

yyEE * YYee

YyEe ( F1)

F1 cross is

YyEe * YyEe

YE Ye yE ye
YE YYEE YYEe YyEE YyEe
Ye YYEe YYee YyEe Yyee
yE YyEE YyEe yyEE yyEe
ye YyEe Yyee yyEe yyee

if the genes assort independently the expected genotypic ratio is

YYEE:YYEe:YyEE:YyEe:YYee:Yyee:yyEE:yyEe:yyee=1:2:2:4:1:2:1:2:1

( phenotype of the double mutant is not given)

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