Question

Some of commercially available buffers are listed below. Which of the following would be the best...

Some of commercially available buffers are listed below. Which of the following would be the best choice to prepare a pH 6.5 buffer solution?

Group of answer choices

CAPS, pKa = 10.4

BICINE, pKa = 8.3

ACES, pKa = 6.8

CHES, pKa = 9.3

HEPES, pKa = 7.6

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Answer #1

For best buffer pH of the buffer should be closest possible to pKa of the acid.

Here pH of buffer is 6.5

So, for best buffer, pKa of the acid should be closest to 6.5

This is true fort ACES

Answer: ACES

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