In its simplest form the Claisen condensation involves the enolate anion of an ester behaving as...
- In its simplest form the Claisen condensation involves the enolate anion of an ester behaving as a nucleophile towards a neutral molecule of the same ester. Illustrate the mechanism of the reaction using ethyl acetate, CH3CO2CH2CH3, as the ester. [5 marks] (b) What base would you use in the reaction ? Explain your choice. [2 marks]
- Name and give the formula of a reagent that you could use to convert benzyl alcohol, C6H5CH2OH, into benzaldehyde, C6H5CHO. In the carbonyl group, oxygen is more electronegative than carbon and the oxygen atom bears two lone pairs of electrons whereas carbon has none. How do these features affect the reactivity of the functional group?
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In its simplest form the Claisen condensation involves the
enolate anion of an ester behaving as...
Claisen Condensations Claisen condensations involve the enolate anion of an ester which acts as a nucleophile...
Claisen Condensations Claisen condensations involve the enolate anion of an ester which acts as a nucleophile attacking another molecule of ester. The resulting product of this reaction is a Beta-ketoester. Draw the enolate anion which serves as the nucleophile in the reaction above. Draw the resonance structure of this enolate. Look at the mechanism of this reaction in your textbook (7^th edition), pages 773-774. What type of reaction does this resemble, S_N1,S_N2, E1, or E2? Ethanol is one of the...
The Claisen condensation converts 2 molecules of an ester into a ?-keto ester. The reaction starts...
The Claisen condensation converts 2 molecules of an ester into a
?-keto ester. The reaction starts with the ester in an
alkoxide/alcohol solution and is worked up with acid to form the
neutral ?-keto ester product.
Please show what goes in each box!! What I put shown below are
all incorrect.
The Claisen condensation converts 2 molecules of an ester into a β-keto ester. The reaction starts with the ester in an alkoxide/alcohol solution and is worked up with acid...
The Claisen condensation converts 2 molecules of an ester into a B-keto ester. The reaction starts...
The Claisen condensation converts 2 molecules of an ester into a B-keto ester. The reaction starts with the ester in an alkoxide/alcohol solution and is worked up with acid to form the neutral B-keto ester product. :0 O: 1. -OCH2CH3/CH3CH20H 2 2. H30 OH Show the curved-arrow mechanism for the Claisen condensation of ethyl ethanoate treated with ethoxide ion. Include all formal charges and nonbonding electrons. In each step, draw only the species that react in that step. If an...
Experimental Outline In its simplest form, the aldol condensation is a self-addition involving tw...
Organic Chemistry 2
Experimental Outline In its simplest form, the aldol condensation is a self-addition involving two molecules of the same aldehyde or ketone, in the presence of a base, and results in the formation of a new carbon-carbon bond joining the carbonyl carbon of one molecule to the a-position of the second. In many cases - if the reaction conditions aren't sufficiently mild - the initially formed aldol product reacts further in an elimination reaction to give what is...
What is the correct name for the following compound? d) 5-oxo-3-octenoic acid What is the defining...
What is the correct name for the following compound? d) 5-oxo-3-octenoic acid What is the defining functional group of a carboxylic acid? a) an-H attached to a carbonyl group b) an-H attached to a carbon-carbon triple bond c) an-OH attached to a carbonyl group d) an -OH group attached to a O-C double bond e) an-OH group attached to an aromatic ring To convert a carboxylic acid to an aldehyde a) convert the acid to an acid chloride, then use...
Claisen Condensations Claisen condensations involve the enolate anion of an ester which acts as a nucleophile attacking another molecule of ester. The resulting product of this reaction is a Beta-ketoester. Draw the enolate anion which serves as the nucleophile in the reaction above. Draw the resonance structure of this enolate. Look at the mechanism of this reaction in your textbook (7^th edition), pages 773-774. What type of reaction does this resemble, S_N1,S_N2, E1, or E2? Ethanol is one of the...
The Claisen condensation converts 2 molecules of an ester into a
?-keto ester. The reaction starts with the ester in an
alkoxide/alcohol solution and is worked up with acid to form the
neutral ?-keto ester product.
Please show what goes in each box!! What I put shown below are
all incorrect.
The Claisen condensation converts 2 molecules of an ester into a β-keto ester. The reaction starts with the ester in an alkoxide/alcohol solution and is worked up with acid...
The Claisen condensation converts 2 molecules of an ester into a B-keto ester. The reaction starts with the ester in an alkoxide/alcohol solution and is worked up with acid to form the neutral B-keto ester product. :0 O: 1. -OCH2CH3/CH3CH20H 2 2. H30 OH Show the curved-arrow mechanism for the Claisen condensation of ethyl ethanoate treated with ethoxide ion. Include all formal charges and nonbonding electrons. In each step, draw only the species that react in that step. If an...
Organic Chemistry 2
Experimental Outline In its simplest form, the aldol condensation is a self-addition involving two molecules of the same aldehyde or ketone, in the presence of a base, and results in the formation of a new carbon-carbon bond joining the carbonyl carbon of one molecule to the a-position of the second. In many cases - if the reaction conditions aren't sufficiently mild - the initially formed aldol product reacts further in an elimination reaction to give what is...
What is the correct name for the following compound? d) 5-oxo-3-octenoic acid What is the defining functional group of a carboxylic acid? a) an-H attached to a carbonyl group b) an-H attached to a carbon-carbon triple bond c) an-OH attached to a carbonyl group d) an -OH group attached to a O-C double bond e) an-OH group attached to an aromatic ring To convert a carboxylic acid to an aldehyde a) convert the acid to an acid chloride, then use...
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