Question

Based on your knowledge of the pathophysiology of respiratory disorders, inflammation, and the adaptive immune system, what do you think the overall pathophysiological mechanism of ARDS is, and what are the current best treatment practices?

Answer 1

Pathophysiological mechanisms of ARDS :

ARDS- Acute respiratory distress syndrome

Is is the condition where the patients experience the respiratory failures. We can see that they have accumulation of fluid in their lungs.

It is caused due to the Trauma to the chest or any infection in our body (sepsis).

mostly seen after the direct injury to the chest. When it occurs there will be fluid formation occurs and it accumulated in the bottom the lungs where we can see the alveoli.

This is used as exchange of gases in our body, the fluid in the Alveoli increases ( Air sac becomes inflamed) . It reduces the function. So the exchange of the gases will get reduced to the blood and body will lack in oxygen(hypoxaemia).

so our heart will work fast to send the blood to the lungs to get more oxygenated blood to the body( Increased heart rate ) when it occurs the person will experience the increased breathing and shortness of breath due to the fluid accumulation in the lungs. So there will be proper inhalation and exhalation process.

TREATMENT:

First they will administer oxygen supply to the patient, because they will not get the adequate oxygen. And they will reduce the inflammation in the lungs. (Ventilation support)

Inflammation in the AIr sac (lungs) will be cleared to through drugs called corticosteroids.

Sometimes there will be any infection over the lungs . To clear the infection antibiotics will be given to the patient.

And also taken care of fluid management.