During the course of development many cells can
undergo epithelial to mesenchymal
transitions and vice versa. When this happens the adhesion of cells
to each other and their
connections to the extracellular matrix changes. This leads to
changes in the transcription
of many genes. Give one example of how a change in cell adhesion or
connection to the
extracellular matrix might cause transcriptional changes through
signaling pathways.
During the course of development many cells can undergo epithelial to mesenchymal transitions and vice versa....
explain 1 or 2 molecular details in how epigenetics may allow melanoma cells to outsmart BRAF inhibitors **This is for a genetics course Seope: This science commentary claims that epigeneties plays a role in cancer cells becoming therapy-resistant. The language used is generalized for the non-scientist and does not include any molecular details, such as methylation of a specific nucleotide in an allele or modification of a specific histone tail amino acid. Your task (individually or in a group of...
1. According to the paper, what does lactate dehydrogenase (LDH) do and what does it allow to happen within the myofiber? (5 points) 2. According to the paper, what is the major disadvantage of relying on glycolysis during high-intensity exercise? (5 points) 3. Using Figure 1 in the paper, briefly describe the different sources of ATP production at 50% versus 90% AND explain whether you believe this depiction of ATP production applies to a Type IIX myofiber in a human....