The main problem with the acylation of enolates is that reaction tends to occur at oxygen...
The main problem with the acylation of enolates is that reaction tends to occur at oxygen rather than at carbon. Why is this not a problem in the aldol reaction?
Homework Answers
First of Aldol addition reaction is an example for Nucleophilic addition. And carbon is more Nucleophilic than oxygen atom in enolate due ti more electronegativity o oxygen atom . Hence Electrophile readily attacks at carbon of enolate rather than oxygen atom
Moreover there is no involvement of acyl group in aldol addition.
During acylation of ketone it is major problem to overcome we use silyl enol ether and enamine as intermediate.
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The main problem with the acylation of enolates is that reaction
tends to occur at oxygen...
1. The reaction web includes most of the reactions of enolates we have studied. The products...
1. The reaction web includes most of the reactions of enolates we have studied. The products of these reactions can be treated with other reagents to generate new functionality - think synthesis! Make up your own examples - e.g. What if you treated compound D with CH,MgBr? In the table, summarize the types of products produced from these reactions. CH3 MgBr acid quench acid quench NaOH, H2O EIO OEt acid quench acid quench acid quench D LIAIHA acid quench acid...
Discussing the person rather than the behavior tends to solve the problem much quicker and helps...
Discussing the person rather than the behavior tends to solve the problem much quicker and helps to build the manager/employee relationship. (2pts) Question 24 - Discussing the person rather than the behavior tends to solve the problem much quicker and helps to build the manager/employee relationship. True False
lab help please!! #6 FRIEDEL-CRAFTS ACYLATION OF FERROCENE 2. This reaction is done with a 10-fold...
lab
help please!!
#6 FRIEDEL-CRAFTS ACYLATION OF FERROCENE 2. This reaction is done with a 10-fold excess of acetic anhydride, yet the dominant product of the reaction is the mono-acylated compound. Very little 1,1'-diacetylferrocene is formed. a. Why? b. What conditions are necessary to form 1,1'-diacetylferrocene as the main product? c. Why does 1,3-diacetylferrocene not form under these conditions?
Friedel-Crafts Acylation of Ferrocene H3PO4 DISCUSSION 1. This reaction is done with a 10-fold excess of...
Friedel-Crafts Acylation of Ferrocene
H3PO4 DISCUSSION 1. This reaction is done with a 10-fold excess of acetic anhydride, yet the dominant product of the reaction is the mono-acylated compound. Very little 1,1'-diacetylferrocene is formed. a. Why? b. What conditions are necessary to form 1,1'-diacetylferrocene as the main product? c. Why does 1,3-diacetylferrocene not form under these conditions? 2. During workup of the product, water reacts with the excess acetic anhydride to give what side product(s)?
Why do ddNTPs in Sanger sequencing serve as terminators of the polymerase reaction? O because they...
Why do ddNTPs in Sanger sequencing serve as terminators of the polymerase reaction? O because they have an extra oxygen in Carbon 3 and no peptide bond can occur with the following nucleotide. O because they lack an oxygen in Carbon 3 and no phosphodiester bond can occur with the following nucleotide. O because they lack an oxygen in Carbon 5 and the polymerase detects that as a termination signal Because they lack a phosphate group in Carbon 5 and...
Aldol Condensation Reaction
Why is the major product between p-anisaldehyde and acetophenone the crossed aldol product rather than the Cannizzaro reaction or the self-condensation ofacetophenone?Please actually explain instead of showing a mechanism. I do know the mechanism but am having a hard time understanding why these two other reactions are not favored.
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Describe a problem that may occur where it would be better to use Access to solve, rather than Excel. Describe the benefits of Access versus Excel.
please help with these chemistry problems 2. (5 points) Why does this reaction occur via a...
please help with these chemistry problems
2. (5 points) Why does this reaction occur via a Si1 pathway and not via a Si2 pathway? 3. (5 points) In general are SN1 reactions stereospecific? Why or why not? 2 5.(5 points) Why do carbon substituents stabilize a carbocation and destabilize a carbanion? 6. (5 points) The mass spec of your product has a base peak at 77 draw what this fragment looks like. What would explain the peak at 79. (you...
Problem Page Question Gaseous butane CH3CH22CH3 reacts with gaseous oxygen gas O2 to produce gaseous carbon...
Problem Page Question Gaseous butane CH3CH22CH3 reacts with gaseous oxygen gas O2 to produce gaseous carbon dioxide CO2 and gaseous water H2O. If 23.9g of carbon dioxide is produced from the reaction of 9.88g of butane and 47.4g of oxygen gas, calculate the percent yield of carbon dioxide. Round your answer to 3 significant figures.
2. Certain addition reactions will occur where the product has a different carbon skeleton than the...
2. Certain addition reactions will occur where the product has a different carbon skeleton than the starting material. Why does this occur? The reaction below is one of those reactions. Predict the major and minor product.(5 pts) CH3 CH3C-C HC CH2 CH3
1. The reaction web includes most of the reactions of enolates we have studied. The products of these reactions can be treated with other reagents to generate new functionality - think synthesis! Make up your own examples - e.g. What if you treated compound D with CH,MgBr? In the table, summarize the types of products produced from these reactions. CH3 MgBr acid quench acid quench NaOH, H2O EIO OEt acid quench acid quench acid quench D LIAIHA acid quench acid...
lab
help please!!
#6 FRIEDEL-CRAFTS ACYLATION OF FERROCENE 2. This reaction is done with a 10-fold excess of acetic anhydride, yet the dominant product of the reaction is the mono-acylated compound. Very little 1,1'-diacetylferrocene is formed. a. Why? b. What conditions are necessary to form 1,1'-diacetylferrocene as the main product? c. Why does 1,3-diacetylferrocene not form under these conditions?
Friedel-Crafts Acylation of Ferrocene
H3PO4 DISCUSSION 1. This reaction is done with a 10-fold excess of acetic anhydride, yet the dominant product of the reaction is the mono-acylated compound. Very little 1,1'-diacetylferrocene is formed. a. Why? b. What conditions are necessary to form 1,1'-diacetylferrocene as the main product? c. Why does 1,3-diacetylferrocene not form under these conditions? 2. During workup of the product, water reacts with the excess acetic anhydride to give what side product(s)?
Why do ddNTPs in Sanger sequencing serve as terminators of the polymerase reaction? O because they have an extra oxygen in Carbon 3 and no peptide bond can occur with the following nucleotide. O because they lack an oxygen in Carbon 3 and no phosphodiester bond can occur with the following nucleotide. O because they lack an oxygen in Carbon 5 and the polymerase detects that as a termination signal Because they lack a phosphate group in Carbon 5 and...
please help with these chemistry problems
2. (5 points) Why does this reaction occur via a Si1 pathway and not via a Si2 pathway? 3. (5 points) In general are SN1 reactions stereospecific? Why or why not? 2 5.(5 points) Why do carbon substituents stabilize a carbocation and destabilize a carbanion? 6. (5 points) The mass spec of your product has a base peak at 77 draw what this fragment looks like. What would explain the peak at 79. (you...
2. Certain addition reactions will occur where the product has a different carbon skeleton than the starting material. Why does this occur? The reaction below is one of those reactions. Predict the major and minor product.(5 pts) CH3 CH3C-C HC CH2 CH3
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