Question

1. Draw and label properly dose-response curves for effective and lethal doses of a toxicant. explain the purpose of such a graphs and the meaning of ED30 and LD50?

2. describe the two main mechanism by which toxicants can contribute to the development of cancer. how can we differentiate between these two mechanism?

3. describe the distribution of a water-soluble toxicants absorbed from a GI trac, taking into consideration the effect of first pass, volume of distribution and blood flow rate.

4.Describe the principle of biotransformation and elimination of toxicants?

Answer 1