Question

BIOCHEMISTRY

please answers the both questions

Q1: Which of the following statements about enzymes are true? (Check all that apply)

A) Enzymes affect the activation energy of the reaction.

b) Enzymes affect the equilibrium position of a chemical reaction.

c) Enzymes affect the Gibbs Free Energy change of a chemical reaction.

d) Enzymes decrease the time needed for a reaction to reach equilibrium.

Q2: What best describes the nature of the active site.

a) It is a rigid pocket that exactly matches the substrate

b) It is a rigid pocket that exactly matches the transition state.

c) It is flexible pocket that binds to a substrate, but changes shape during the course of the reaction.

d) It is pocket that always uses ATP to provide the energetic driving force to make reactions happen.

Answer 1

1. The answers are a and c.

1. Enzymes affect the activation energy of the reaction.

Enzymes decrease the activation energy of a reaction. So that, the reaction rate becomes faster.

C)Enzymes affect the Gibbs Free Energy change of a chemical reaction.

Enzymes lower the Gibbs free energy and thus activation energy reduces.

Please note that enzymes do not disturb the equilibrium state of a reaction.

2. The answer is a.

1. It is a rigid pocket that exactly matches the substrate

Active site is rigid in nature and only the substrate complementary to the shape of the site able to enter into the space.