Question

he Urea cycle and Citric Acid cycle have two molecules that are shared. Describe these two metabolites and which enzymes use them.

Answer 1

Two intermediate which are common in Urea as well as in TCA cycle are

Oxaloacete and aspartate

Arginosuccinate synthase, condense both citrulline and aspartate ( form by tramsamination of oxaloacete) and form arginosuccinic acid. This later upon cleavge form arginine and fumarate. This fumarate channels to TCA cycle. Where it converted to oxaloacete by using funerase and malware dehydrogenase.  

Apart of this Co2 produced in TCA cycle , utilized in Urea cycle.

ATP produce in TCA is also utilized in urea cycle.