Secretory proteins move from the cis to the medial to the trans Golgi which are discrete compartments or cisternae flanked by smaller vesicles. Which model for Golgi trafficking takes into account the observation that secretory proteins are not observed in the flanking vesicles?
A. Orthogonal compartment model. B. Transverse secretory model. C. Cisternal maturation model. D. Vesicle transport model. E. ERGIC model.
Answer:
Which model for Golgi trafficking takes into account the observation that secretory proteins are not observed in the flanking vesicles?
Explanation: There are two main models of transport through golgi apparatus: Vesicle transport model and Cisternal maturation model. Vesicle transport model involves the role of flanking vesicles in association with golgi apparatus in transport of proteins and cisternae are considered stationary through the transport process. Cargo is transported through the flanking vesicles. On the other hand, based on Cisternal maturation model, golgi apparatus is a more dynamic structure and cis cisternae transverse the golgi stack and mature to become trans cisternae.
Secretory proteins move from the cis to the medial to the trans Golgi which are discrete...
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