1. Bupropion hydrochloride is a widely used antidepressant marketed under the name of Wellbutrin. Starting from benzene design a synthesis for Wellbutrin using any reactions we have learned this year. This could involve a number of steps.
1. Bupropion hydrochloride is a widely used antidepressant marketed under the name of Wellbutrin. Starting from...
Problem 3 Propose a synthesis of the following molecule from the given starting material. You may use any reactions we have learned in this course so far, and any reagents containing the carbon atoms you need. If you make a mixture in any of the steps, place a box around the compound you would separate from the mixture, and carry on with your synthesis assuming you can isolate the desired regioisomer. NH2
Starting from Benzene and using reagents that we have discussed in class, design a synthesis for the Target molecule (TM). TM SM
Question 1 (12 marks) Design a synthesis which uses the starting material indicated to synthesize the product in the scheme below. You may use any reactions we have learned in 2220 so far, and any reactions from 2210. There is no maximum or minimum numbers of steps, though you should strive for 'conciseness' in your synthetic route. You should note the relative stereochemistry of any substituents and take that into account when designing your synthesis. For each reaction, be sure...
provide a synthesis for the target molecule shown. н" TM SM Bonus: (10 pts) Starting from Benzene and using reagents that we have discussed in class, design a sy molecule (TM).
1. Provide a synthesis of the thio-ether shown below starting from the terminal alkene given (using reactions we have learned in class it will take more than one step!). Show a mechanism for each step of this reaction.
Question 2 (12 marks) Design a synthesis which uses the starting material indicated to synthesize the product in the scheme below. You may use any reactions we have learned in 2220 so far, and any reactions from 2210. There is no maximum or minimum numbers of steps, though you should strive for 'conciseness' in your synthetic route. You should note the relative stereochemistry of any substituents and take that into account when designing your synthesis. For each reaction, be sure...
CH3 SM TM Bonus: (10 pts) Starting from Benzene and using reagents that we have discussed in class, design a synthesis for the Target molecule (TM). На C NH2 но. ? ОН TM SM
Name 4. Starting with cyclohexene and acetylene as the only source of carbons, show a synthesis of the compound below. 1. Show how you could make the given product from the given starting material. Show all steps. OH a CECH 2. Starting with acetylene and methyl bromide as your only source of carbons show a synthesis of cis-2-butene. 5. Prepare 2-methoxy-propanol from 1-bromo-propane. Show the steps and use any reagents you need. 3. Using acetylene and propyl bromide as your...
1 synthesis for each of the following compounds. Some problems have more than one plausible Starting from benzene and using any other necessary reagents of your choice, design a answer (a) NO2 (b) Н-N, (c) Н.N. (d) (e) Br COOH (f COOH
Starting from benzene and using any other necessary reagents of your choice, design a synthesis for each of the following compounds. Some problems have more than one plausible 1. answer (g)* in this example, what can be done to minimise the amount of the meta/para isomes. NO2 (h) रेर Br (i) Н-N. Br NH2 (k) Br "SoH