All things being equal, and assuming no perturbation of PKas by an enzyme, what two amino...
All things being equal, and assuming no perturbation of PKas by
an enzyme, what two amino acids
would be the only choice for general acid-base catalysis at pH 7.4?
Why?
Homework Answers
Aspartic Acid (D) and Glutamic Acid (E) should be prefered amino acids.
Aspartic acid and Glutamic acid are acidic amino acids (with pI 2.7 and 3.2 respectively) therefore, N terminals of these amino acids will work as nucleophile in the basic medium (@ pH 7.4) and will catalyze the Acid - Base hydrolysis.
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All things being equal, and assuming no perturbation of PKas by
an enzyme, what two amino...
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The HIV protease enzyme uses a general acid-base catalysis mechanism to cleave viral polypeptides but does...
The HIV protease enzyme uses a general acid-base catalysis mechanism to cleave viral polypeptides but does not use a covalent catalysis. This enzyme functions optimally in the pH range of 4-6. Due to the specific amino acids involved in this catalysis, HIV protease is a member of which subclass of proteases? Select one: A. metalloproteases B. aspartyl proteases C. serine proteases D. lysine proteases E. cysteine proteases
1. Enzymes catalyze reactions by diverse mechanisms, frequently involving multiple steps. Consider the well-studied enzyme called...
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single letter abbreviation of all amino acids that correspond 4. Amino acids. The side chains of...
single letter abbreviation of all amino acids that
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of alanine has a pk of 9.87. What is the 153, The amino group charge on...
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The HIV protease enzyme uses a general acid-base catalysis mechanism to cleave viral polypeptides but does not use a covalent catalysis. This enzyme functions optimally in the pH range of 4-6. Due to the specific amino acids involved in this catalysis, HIV protease is a member of which subclass of proteases? Select one: A. metalloproteases B. aspartyl proteases C. serine proteases D. lysine proteases E. cysteine proteases
single letter abbreviation of all amino acids that
correspond
4. Amino acids. The side chains of amino acids have a wide spectrum of chemical and physical properties. In each sp. provided below, write the single-letter abbreviations of all amino acids that match the description positively charged side chains at pH 7.4 negatively charged side chains at pH 7.4 negatively charged side chains at pH 12 achiral contains two chiral carbons side chain restricts the rotation of main chain contains carboxamide...
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