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1) Calculate the free energy required to move 1 mol of K+ ions from the outside...

1) Calculate the free energy required to move 1 mol of K+ ions from the outside of the cell (where [K+] = 3.1 mM) to the inside (where [K+] = 135 mM) when the membrane potential is -78 mV and the temperature is 34.2°C. Give your answer in kJ/mol.

2) Calculate the rate enhancement that could be accomplished by an enzyme forming one low-barrier hydrogen bond that has a free energy of -45 kJ/mol with its transition state at 31°C.

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