1. Animal cells have a Na,K pump that couples the energy of ATP hydrolysis to transport 3 Na ions out of the cell and 2 K ions into the cell. Inside astrocytes, the concentration of Na is 20 mM and th...
1. Animal cells have a Na,K pump that couples the energy of ATP hydrolysis to transport 3 Na ions out of the cell and 2 K ions into the cell. Inside astrocytes, the concentration of Na is 20 mM and the concentration of K is 130 mM. The extracellular concentrations of Na and K are 145 mM and 5 mM, respectively. Calculate the energy required for the transport of Na and K , with this stoichiometry; assume that the cell is at 37 °C and the membrane potential is 50 mV (inside negative). Provide your answer in kJ/mol.
2.The free energy of hydrolysis of ATP under physiological
conditions is -52 kJ/mol. How
many ATP's are required to pump the 3 Na+ ions and 2 K+ ions
described above?
Homework Answers
2ATP s are required to transport 4 moles of K+ out of the cell and 6 moles of Na into the cell
Total energy required is 57*2 = 114kJ
For transportation of 3Na and 2 k ions 1 ATP is required hence teh energy is -52kJ/ mol
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1. Animal cells have a Na,K pump that couples the energy of ATP hydrolysis to transport 3 Na ions out of the cell and 2 K ions into the cell. Inside astrocytes, the concentration of Na is 20 mM and th...
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Demonstrate that hydrolysis of ATP to ADP provides enough energy to
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If the Na concentration outside the cell ([Na ]out) is 155 mM and
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