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4. a) Discuss on RNA editing and its impact in cephalopods. (10 Marks) b) Following 5...

4. a) Discuss on RNA editing and its impact in cephalopods. (10 Marks)

b) Following 5 sequences are needed to be aligned using ClustalW method. (15 Marks)
S1: AGGCTATG
S2: TGCCTTAG
S3: GTTGCTTA
S4: ATGCTTAG
S5: CTGCTCAG

i. Build the distance matrix D for the sequences.
ii. Step by step build the rooted guide-tree using UPGMA approach.

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Answer #1

RNA editing effect on cephalopods:-

  • It slows down cephalopod evolution.
  • In RNA editing nucleotide sequence is changed without changing the original DNA sequence.
  • In cephalopods it is found that editing provide much adaptable population.
  • It provided fitness advantage.
  • Editing in cephalopods have decreased R/ C ratio ( ratio of radical to conservative amino acid substitutions)
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