Question

Create an comprehensive response to the following:

• Antimicrobial agents work on a multitude of microbes (bacteria, viral, fungal, parasitic, helminths) and with a variety of mechanisms such as blocking cell wall, protein, or nucleic acid synthesis for the rapidly growing microbes.
• For this discussion assignment, select a antimicrobial agent of your choice and describe the target microbe(s), the mechanism of action, side effects, and treatment regimen.

Please answer entirely with a typed response, only those with a source included will be rated!

Answer 1

PENICILLIN : it is the antimicrobial agent which belongs to class of beta lactams antibiotics

Source: penicillium mould fungi

Target microbes: streptococcus , staphylococcus , clostridium, listeria , Neisseria, treponema , leptospira , bacillus anthracis etc.

Mechanism of action: penicillin is a bactericidal antimicrobial. it kills the bacteria by inhibiting the enzyme transpeptidase. as a result of which it inhibits the cell wall synthesis of the bacteria. the crosslinking of peptidoglycan is prevented which makes cell wall weak . this cause cell wall to break down easily.

Side effects: headache, nausea, vomiting, black discoloration of tongue, urticaria, diarrhoea, stomach pain, allergic reaction etc.

Treatment regimen: penicillin G procaine doses in adults:

streptococcal infection: 600,000-1,000,000 units im qDay for atleast 10 days

staphylococcal infection: 600,000-1,000,000 units im qDay

bacterial endocarditis: 600,000-1,000,000 units im qDay

syphilis : primary , secondary , latent : 600,000 units im qDay for 8 days