Deinococcus radiodurans is probably the world’s toughest bacterium (first discovered growing in ground meat that had been “sterilized” by radiation), able to withstand doses of ionizing radiation ~3000 times greater than those that are lethal to humans. It was also discovered that D. radiodurans has a particularly large number of genes that encode for DNA repair proteins and multiple (4 to 10) copies of its closed circular genome per cell. It has been hypothesized that these multiple dsDNA copies of the genome are aligned and stacked like coins. How would this spatial arrangement help D. radiodurans efficiently repair its DNA?
Deinococcus radiodurans was first toughest bacteria found till now and it was discovered in 1956 in a can of ground meat ,this bacteria is popular due to its highly resistance property to resist radiations.it has been known to withstand radiation level up to 1,000 times that which could kill a human .radiodurans also having a special amazing repair capablities ,due to the formation of multiple copies of each gene are found on all the chromosomes and plasmid.D.radiodurans is a gram positive bacteria ,due to the formation of 4-10 copies of all its gene at any given time depending on its current stage of growth ,this property may be helped bacteria to withstand so much radiations.ReCo is essential for dna damage rapair in Deinococcus radiodurans,due to extraordinary property of D radiodurans ,it can reconstruct a functional chrosomes from hundered of shattered dna fragments within hours ,it is believed that RecA dependent homologous recombination DNA repair plays a vital role in the genome restitution of this organism.
Deinococcus radiodurans is probably the world’s toughest bacterium (first discovered growing in ground meat that had...