If amino acid is acidic in nature then it will have ionizable group, and if it is basic amino acid then also it will have ionizable group,
For acidic amino acid: check if it has more than one -COOH group, if yes it will be acidic
For basic amino acid: check if it has more than one Amine group (NH or NH2 group) if so then it will be basic in nature,
A neutral amino acid has equal number of COOH group and amine group.
How would I know whether a given amino acid has an ionizable group or not? please...
What is isoelectric point? The amino acid glycine has two ionizable groups: 1) a carboxyl acid group with a pKa of 2.72 and 2) an amino group with a pKa of 9.60. Calculate the pI of glycine.
How would you use the titration curve to figure out how many ionizable protons are on an amino acid? Hint: is the titration curve a straight line or did the slope vary? If the slope varied, what was the significance of the slope changes? Is the completely uncharged form of any amino acid ever seen; in other words, can the uncharged amine group and the uncharged carboxylic acid group ever exist at the same pH? Explain your answer
Look up the exact pKa's of the two ionizable groups for the amino acid methionine. a) fill out a table that gives the charge on each ionizable group and the overall charge on the amino acid for eacu whole pH unit from 0 to 12 b) calculate the isoelectric point of met exactly c) compare your calculated pI from (c) with your table. d) draw the structure of the amino acid at pH 0, 7.4, and 12.
4. Which amino acid could form ionic interactions? Explain how you know. 1. Circle the funct tional groups on the R-group of the AMINO ACIDs below that are capable of forming hydrogen bonds. How do you know? 2 4 CH H,C CH, 2. List at least 2 amino acids (numbered 1-10 above) capable of interacting with water 5 and 7 3. List at least 2 amino acids that water would avoid interacting with. Explain how you know. I and 2...
How do you determine the reactivity of an amino acid group? How would I compare them?
Lecture 3 Identify amino-/carboxy termini, and R-group on amino acid What is chirality? Identify a carbon that is chiral (i.e., has 4 different groups attached) Chiral compounds rotate plane polarized light Memorize amino acid 1) structure, 2) classification (hydrophobic, aliphatic, aromatic, negatively charged, positively charged, polar uncharged) Be able to draw glycine (the generic amino acid) Given an amino acid structure and pKas of ionizable groups, be able to determine the charge at pH 1, pH 14, and pH 7...
Given a protein amino acid sequence (written out, 1 letter abbreviation, about 700 amino acids), how do i identify the N and C terminals? I know that N terminal is a free amine group and C is a free carboxyl group, but how do i know it is free? How do i identify it?
Suppose you have a peptide composed of 4 amino acids bonded together: glutamine, glycine, glutamic acid, and the novel amino acid friendsamine, which has an ionizable side group with a pKa of 5.9. At pH 7.0, this peptide has a net charge of -2. What is the charge on the protonated form of the friendsamine side group? Explain how you determined the charge on the protonated friendsamine side group
How many ionizable groups are found in a) serine ? b) arginine ? c) glutamate? d) tyrosine? please show the ionizable for each amino acid. groups
please explain 55. At its isolectric pH, glycine will have both of its ionizable functional groups dissociated. neither of its ionizable functional groups dissociated only its carboxyl group dissociated. only its amino group dissociated. a. b. c. d.