Question

Could you please explain 52 and 53?

section S. Short Answer and Problems (points indicated). Clearty write weur work for following in the space provided. Include units where appropriate. Show Section 5 Points: Clearly write the answer to each of the your work for full credit. 52. (4 points) Explain why purines are salvaged at a greater 53. (3 points) A protein sequence has a region with several Ala, Met, and leu residues spaced 3-4 apart. Do you think it Is likely that this region will form an a-helix? Explain why or why not moleculis 54. (4 points) Describe the two functions of Bycogenin. 2.) Cad

Answer 1

52.) Purines are salvaged at a greater rate than the pyrimidines.Pyrimidines are mainly synthesized through denovo pathways an purine synthesis takes place mainly by salvage pathways and metabolic defects in salvage pathways of purine have been found to be associated with several disorders of metabolism.

53.) The region will form an alpha helix.

An alpha helix has 3.6 residues per turn and the side chain of the amino acids forming the alpha helix have a tendency to change from hydrophobic side chains to hydrophilic side chains with a 3-4 residue periodicity. This is because an alpha-helix is generally located along the outer side of a protein.So Ala,Met and Leu have high tendencies of forming alpha helix.