Question

For each of the complex lipids below, choose (A) if the lipid concentration will increase or (B) if the lipid concentration will decrease when phosphatidic acid phosphatase is constitutively active.

_____ Phospholipids made via strategy #1

_____ Phospholipids made via strategy #2

_____ Phosphatidate

_____ Triacylglycerol

Strategie #1: activate diacylglycerol

Strategie #2: Activate alcohol

Answer 1

Lipid concentration will increase phospholipid made via strategy 1, phosphatidate as well as via triacylglycerol.

• Diacylglycerol acts as an intermediate in lipid synthesis, in the formation of triacylglycerol TAGs from phosphatidate, in the endoplasmic reticulum of liver via TAG synthase
• The formed liver TAG is transported to muscle to be used as fuel or stored in adipose tissue as fat.

Lipid concentration will decrease phospholipid made via strategy 2