Question

e dbruptly discontinuing beta blockers for hypertension without the patient taking another anthypertensive, what might occur? Explain how these adverse effecets can be avoided. Mr. George's blood glucose is 229. His drugs for controlling hypertension are changes to prazosin 10 mg three times a day. His cholesterol and LDL are elevated. His serum potassium level is 3.2 mEq/L 9. Why was Mr. George's hydrochlorothiazide and atenolol discontinued? Explain your answer 10. What type of antihypertensive is prazosin? Explain the physiologie action of prazosin for lowering blood pressure. 11. Does prazosin have an effect on the blood glucose level? What effect could prazosin have on Mr. George's abnormal lipid levels? Explain your answer Mr. George's ankles have become edematous. Hydrochlorothiazide is preseribed. 12. Why hydrochlorothiazide is again added to the drug regime? 13. Prepare a list of antihypertensive drugs that can cause sodium and water retention Reviewed 3/19

Answer 1

9. In the present scenario, Mr.George blood glucose level is 229 and cholesterol and LDL level are increased and serum potassium level is 3.2mEq/L and already he is taking the medication such as hydrochlorothiazide and atenolol discontinued because I think the hydrochlorothiazide and atenolol are not having much more positive effects on Mr.George. May he have effects such as nausea and vomiting thus results in decreased potassium and as well as his cholesterol and LDL are elevated.

10. Prazosin is a competitive alpha-1 adrenergic receptor blocker. By blocking alpha-1 receptors on muscle cells that surround blood vessels, prazosin causes vasodilation (widening) of the blood vessels and consequently decreases the resistance of blood flow. The overall benefit of its use is a decrease in blood pressure.

11. Prazosin treatment effectively reduced blood pressure without compromising diabetic control. Thus we can say that prazosin is not having the effects on the blood glucose level. Prazosin is not having any effects on total cholesterol, high-density lipoprotein cholesterol and triglyceride levels when compared with baseline measurements.

12. During the process of treatment, the patient ankle is edematous and hydrochlorothiazide is again added to the treatment regimen. It helps to treat fluid retention(oedema).

13. Hypertension, also known as high blood pressure, makes the heart work harder to pump blood. This damages the blood vessels and increases the risk of serious complications. Treat high blood pressure with beta-blockers, angiotensin receptor blockers, diuretics, calcium channel blockers, vasodilators and ACE inhibitors. Anytime the blood pressure decreases, the kidneys release an enzyme called renin. Renin splits angiotensin into two substances known as angiotensin I and angiotensin II. Angiotensin II signals the adrenal glands to release a hormone called aldosterone. Aldosterone signals the kidneys to excrete potassium and retain sodium. The sodium causes water retention and increased blood volume.