Homework Answers
1.Ion channels involved in the generation of the action potential.
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Ion channels are involved with generating action potentials. Below is an electrical profile of a neuronal action potent...
CNCORA 6 of 10 > Action potentials in neurons involve opening and closing of voltage-gated Nat...
CNCORA 6 of 10 > Action potentials in neurons involve opening and closing of voltage-gated Nat and K ion channels. Place the events of an action potential in order, starting and ending with a cell at its resting membrane potential. Resting state Return to resting state Answer Bank A graded potential brings the membrane to threshold potential. Fast Na+ and slow K* channels are activated. Nat rushes into the cell, causing membrane depolarization. K channels close slowly, resulting in hyperpolarization....
3. Many neurons contain "delayed K channels". Like voltage-gated Nat channels, these voltage-gated K+ channels open in response to a rise in membrane potential and then undergo inactivati...
3. Many neurons contain "delayed K channels". Like voltage-gated Nat channels, these voltage-gated K+ channels open in response to a rise in membrane potential and then undergo inactivation. However, opening of the voltage-gated K channels lags behind opening of the voltage-gated Na channels. a) Why does neuronal function require the voltage-gated K channels to open more slowly than the voltage-gated Na channels? b) Compared to a neuron that lacks voltage-gated K channels, what differences would you expect in the shape...
An action potential does not move back wards in the axon because.. a.Voltage-gated sodium channels behind...
An action potential does not move back wards in the axon because.. a.Voltage-gated sodium channels behind the action potential are inactivated. b. Potassium leak channels no longer let potassium ions through c. Voltage-gated sodium channels are open d. Mechanically-gated channels prevent outflow of sodium e. Voltage-gated potassium channels are closed
The fixed pattern of changes in membrane potential during an action potential is coordinated by the...
The fixed pattern of changes in
membrane potential during an action potential is coordinated by the
sequential opening and closing of voltage-gated ion channels. Can
you identify the status (open/closed) of the voltage-gated Na+ and
K+ channels during each phase of an action potential? Drag the
appropriate labels onto the graph to indicate the status (open or
closed) of the voltage-gated Na+ and K+ channels during each phase
of an action potential. Labels may be used once, more than once,...
Voltage-gated Na channels exist in three distinct conformations in axons because Answers A-D A they assume...
Voltage-gated Na channels exist in three distinct conformations in axons because Answers A-D A they assume an inactivated conformation shortly after opening, which ensures that the action potential cannot move backwards toward the cell body. B they change conformation when binding Nat and transporting it to the opposite side of the membrane before releasing it outside the cell. C they respond to ligand binding, mechanical stress, or changes in voltage. D they assume different conformations as ATP is bound and...
During the propagation of an action potential, what would be the effect of a mutation in...
During the propagation of an action potential, what would be the effect of a mutation in the voltage-gated Na+-channels that does not allow “inactivation” phase to occur, such that these channels go directly from open to closed conformations? a) The neuron with the mutant Na+ channels will start letting in calcium ions and generate a calcium-based action potential that is stronger than the sodium-based action potential. b) The neuron with the mutant Na+ channel will exhibit a reverse electrochemical gradient...
You are studying the permeability on Voltage-Gated Sodium Channels involved in action potential generation. Predict what...
You are studying the permeability on Voltage-Gated Sodium Channels involved in action potential generation. Predict what would happen to the permeability of Sodium in the following cases (would it decrease, increase or stay the same?). Explain why you chose your answer. i.Increased receptor number. ii. Add a drug that make channel stay open longer. iii. Raise Vm above+35mV. iv.Lower Vm below -70mV. v.Add a drug that prevents channel opening. vi. Add more Na+ to the extracellular environment.
**Please answer everything and don't write in cursive, high rating will be given out** 1. For...
**Please answer everything and don't write in cursive,
high rating will be given out**
1. For each of the statements below relating to action potentials, fill in the blank with the correct ion: Ca++, K+, Nat, or Cl-. (5 points) At resting potential, the equilibrium voltage is maintained in part by chloride ions and other anions inside the cell and by the action of the the pump, there is a higher concentration of concentration of pump. Because of the action...
The Nat -k* pump uses the energy of Nat moving down its concentration gradient to pump...
The Nat -k* pump uses the energy of Nat moving down its concentration gradient to pump k up its concentration gradient. Answers A-B A True B False Voltage-gated Na* channels exist in three distinct conformations in axons because Answers A-D A they assume an inactivated conformation shortly after opening, which ensures that the action potential cannot move backwards toward the cell body. B they change conformation when binding Nat and transporting it to the opposite side of the membrane before...
2. Neuron during an action potential: a. What triggers the first action potential (which ion)? b....
2. Neuron during an action potential: a. What triggers the first action potential (which ion)? b. What is the typical threshold potential of a neuron? c. The calculated equilibrium potential of Na+ (EN) is approx. +60mV (calculated). Explain how this is related to the rising phase of an action potential (depolarization). d. The calculated equilibrium potential of K+ (EK) is approx. -90mV. Explain how this is related to the falling phase (repolarization). e. Direction of Nation movement (influx/efflux). f. Direction...
CNCORA 6 of 10 > Action potentials in neurons involve opening and closing of voltage-gated Nat and K ion channels. Place the events of an action potential in order, starting and ending with a cell at its resting membrane potential. Resting state Return to resting state Answer Bank A graded potential brings the membrane to threshold potential. Fast Na+ and slow K* channels are activated. Nat rushes into the cell, causing membrane depolarization. K channels close slowly, resulting in hyperpolarization....
3. Many neurons contain "delayed K channels". Like voltage-gated Nat channels, these voltage-gated K+ channels open in response to a rise in membrane potential and then undergo inactivation. However, opening of the voltage-gated K channels lags behind opening of the voltage-gated Na channels. a) Why does neuronal function require the voltage-gated K channels to open more slowly than the voltage-gated Na channels? b) Compared to a neuron that lacks voltage-gated K channels, what differences would you expect in the shape...
The fixed pattern of changes in
membrane potential during an action potential is coordinated by the
sequential opening and closing of voltage-gated ion channels. Can
you identify the status (open/closed) of the voltage-gated Na+ and
K+ channels during each phase of an action potential? Drag the
appropriate labels onto the graph to indicate the status (open or
closed) of the voltage-gated Na+ and K+ channels during each phase
of an action potential. Labels may be used once, more than once,...
Voltage-gated Na channels exist in three distinct conformations in axons because Answers A-D A they assume an inactivated conformation shortly after opening, which ensures that the action potential cannot move backwards toward the cell body. B they change conformation when binding Nat and transporting it to the opposite side of the membrane before releasing it outside the cell. C they respond to ligand binding, mechanical stress, or changes in voltage. D they assume different conformations as ATP is bound and...
**Please answer everything and don't write in cursive,
high rating will be given out**
1. For each of the statements below relating to action potentials, fill in the blank with the correct ion: Ca++, K+, Nat, or Cl-. (5 points) At resting potential, the equilibrium voltage is maintained in part by chloride ions and other anions inside the cell and by the action of the the pump, there is a higher concentration of concentration of pump. Because of the action...
The Nat -k* pump uses the energy of Nat moving down its concentration gradient to pump k up its concentration gradient. Answers A-B A True B False Voltage-gated Na* channels exist in three distinct conformations in axons because Answers A-D A they assume an inactivated conformation shortly after opening, which ensures that the action potential cannot move backwards toward the cell body. B they change conformation when binding Nat and transporting it to the opposite side of the membrane before...
2. Neuron during an action potential: a. What triggers the first action potential (which ion)? b. What is the typical threshold potential of a neuron? c. The calculated equilibrium potential of Na+ (EN) is approx. +60mV (calculated). Explain how this is related to the rising phase of an action potential (depolarization). d. The calculated equilibrium potential of K+ (EK) is approx. -90mV. Explain how this is related to the falling phase (repolarization). e. Direction of Nation movement (influx/efflux). f. Direction...
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