Question

1-Glycoprotien IIB/IIIa plays a major part in which of the follwoing platelet action?

A)aggregation B)activation C)aversion D)adhesion

2-which of the follwoing is considered a potent aggregator, increasing platelet adhesion?

A)prothrombin B) thrombin C)prostaglandin D)nitric oxide

3- which of the follwoing is produced by the liver and acts as an inhibitor of coagulation binding with thrombin/

A)Serotonin B) thrombin C)prostaglandin D)anti-thrombin

4-Cell-to- cell adhesion continued formation of platelet plug through binding of fibrinogrn is part of which platelet funtion stage?

A)aggregation B)activation C)aversion D)adhesion

Answer 1

Ans 1: Platelet aggregation.

Platelet aggregation is mediated by glycoprotein IIB/IIIa.This glycoprotein complex bindsplasma proteins such as fibrinogin, fibronectin,von willebrand factor and vitronectin.

Ans 2: Thrombin

It is a potent platelet agonist acts via dual system of glycoprotein coupled protease activated receptors,

Ans 3: Anti Thrombin

Anti Thrombin is a glyco protein produced by liver inhibits the activitity of most activated coagulation factors.

Ans 4: aggregation

cell to cell adesion and formation of platelet plug through fibrinogin is part of platelet aggregation.