Question

d.) You would like to find a drug that slows the ability of Wnt signaling to activate its target genes. Beta catenin is not a very good target for drug discovery, because it is difficult to find drugs that specifically block a protein from binding to DNA or to other proteins. Suggest another way a hypothetical drug can block this pathway. Explain briefly what your drug will bind to, and how this reaction will end up affecting the rate of beta catenin nuclear import. (6 points)

Answer 1

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