Which patient would you expect to have the poorest metabolism of a medication? and why? a. patient on kidney dialysis b....
Which patient would you expect to have the poorest metabolism of a medication? and why?
a. patient on kidney dialysis
b. patient w/ alcoholic cirrhosis
c. patient w/ skull fracture?
d. patient w/ intestinal cancer
Homework Answers
Poorest metabolism of medication occurs in the patient with alcoholic liver cirrhosis. because the liver has a great role in the metabolism of medication. Metabolism consists of anabolism and catabolism of drugs (Biotransformation of the drug) which is nessesary for body to use the drug and which also helps in the elimination of drug. In cirrhosis of the liver, liver cells are damaged and gradually cells are transformed into scar tissue. A damaged liver can not able to metabolize the drug.
Patients on kidney dialysis may have a problem in excretion but the kidney does have any role in the metabolism of the drug.
Patients with a skull fracture or even brain damage do not have any effect on drug metabolism.
Patients with intestinal cancer may have a problem with the absorption of drug particle but there is no issue with metabolism.
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