Question

1. The following table lists data from a volunteer weighing 55 kg administered a 300mg dose (IV bolus). Samples were drawn at the times indicated and plasma concentration of drug was measured.

time(hrs)	Cp (mg/L)
1	12.95
2	10.3
3	7.96
4	6.43
6	4.2
10	1.75
12	1.2

Calculate Kel from the data. Hint: y = mx + b

What is the t_1/2

What is the C₀?

What is the apparent volume of distribution Vd?

What is the Cl_TB?

Answer 1