Lecture Questions Determine if each of the following reactions is Sn1 or SN2. Then predict the products: L Nao OTS...
Q. Predict mechanism type (SN1, E1, SN2, E2) for the following reactions. If more than one is possible, predict which mechanism is more likely and explain why. 5 - HI ح . 0H SNI KOCH2CH3 KOCHCH - I want to wors. NaOH, H2O, 100°C في NaCN ي . HO )..NC دا SN2
Please show the mechanism showing all possible substitution products. SN1 and SN2 only. Thank you. Determine the major substitution product(s) for each of the following reactions. In addition, please state the mechanism that is employed in the formation of each product. (8 points) Br NaOCH 3 CH3OH H20 Heat
Question 5 Predict the major and minor products for the following reactions: NaSH НАС NaOET men major Question 6: Predict the major and minor products for the following reactions: NaOEt OTS With A - Tosylate (OTS) 0 NaOH 1 Question : Draw the plausible mechanism for each of the following transformations: CH HGC by b) HC conc. H,SO heat CH
3. Complete each of the following reactions. Draw the structure of the organic product or products in the space provided. Show stereochemistry if appropriate. (3 points each) SN2 reaction (a) (CH3)CHCH2Cl + NaCN Sn1 reaction (b) (CH3)CHCH,CI + NaCN (C) M Sn2 reaction ¢l + NaOH - ACH. E1 reaction (d) (CH3)3CCH,OH + HCI major product Ez reaction Cl + NaOH - LCH3 н Ereaction Cl + H20
predict the mechanism (Sn1, Sn2, E1, E2) and major products for each reaction 8) NaOCHy CH,CHE CH,OH CH CH heat H,PO heat KOB HOIBU CHO CH, NaN. Br. H NaOCH CH3CH2OH heat dapted from Ruehl
Question : Predict the major and minor products for the following reactions: NASH -CH3 + 1 H30 HC b) NaOEt Question 6: Predict the major and minor products for the following reactions: NaOEt OTS - Tosylate (OTS) With on CHM 2210 CH3 NaOH H₂C O=O=O Question 7: Draw the plausible mechanism for each of the following transformations: CHE BECH HO HBr CH CH CH3 H₂C- conc. H,SO heat HC Insuu H Question 8 Which is the better retrosynthesis for the...
3. Shown below are a series of reactions. Predict the major product for each of them. Remember, you will need to first decide whether the reaction occurs by an SN2, SN1, E2, or E1 before you can determine what the product will be. Label each as SN2, SN1, E2, or E1. Hint: First decide whether S2/E2 or S1/E1 is favored, and then decide whether the reaction pathway goes by a substitution or elimination reaction. SN2 / SN1 E2/E1 Na DMSO,rt...
Determine whether each of the following reactions occur through an SN1, SN2, E1, or E2 mechanism. Determine whether each of the following reactions occur through anSN1,SN2,E1 or E2 mechanism
2 Ws 1. For each of the following SN2 reactions, (i) draw the chemical reaction (reactants and products) (ii) show the proper mechanism (iii) draw the transition states a. (S)-2-chlorobutane and NaSH b. (R)-3-iodohexane and NaOH c. (R)-2-bromohexane and NaCN d. 1-bromocycloheptane and NaOH e. Ethyl iodide and sodium actate (CH:CO2Na) Br NaOH Na o NaOH Br NaCN DMF ONA 1,2-dibromoethane Nao
Determine whether each of the following reactions occurred through an SN1, SN2, E1, or E2 mechanism.