Draw the product formed by the reaction of potassium t-butoxide with (1S,2S)-1-bromo-2-methyl-1-phenylbutane (shown below). (Draw the correct stereoisomer of the product.)
A reaction is given whose product needs to be drawn. Firstly, identify whether the product formed through substitution reaction or the elimination reaction then, write the product formed.
Thus, identify the nucleophile and the leaving group in the given reaction and accordingly form the product of the reaction.
Elimination reaction can be categorized as, and depending on the type of mechanism followed.
• reaction is unimolecular elimination reaction which takes place between a haloalkane and a nucleophile. The reaction takes place in two step through a carbocation intermediate. In haloalkane, the order of reactivity for the reaction is, like the stability of carbocation.
• reaction is bimolecular elimination reaction which takes place between a haloalkane and a nucleophile. The reaction takes place in one step through a transition state. Consider the following scheme of a reaction:
In haloalkane, the order of reactivity for the substitution reaction is, .
Substitution reaction can be categorized as, and depending on the type of mechanism followed.
• reaction is unimolecular nucleophilic substitution reaction which takes place between a haloalkane and a nucleophile. The reaction takes place in two step through a carbocation intermediate.
In haloalkane, the order of reactivity for the substitution reaction is, like the stability of carbocation.
• reaction is bimolecular nucleophilic substitution reaction which takes place between a haloalkane and a nucleophile. The reaction takes place in one step through a transition state.
In haloalkane, the order of reactivity for the substitution reaction is, .
Identify the structure of haloalkane and strength of nucleophile in the given compound as shown below:
As secondary haloalkane is present in the presence of strong nucleophile, that is, tertiary butoxide in polar aprotic solvent. So, the reaction will proceed through Elimination mechanism.
Write the product of the given reaction following the E2 mechanism with the correct stereochemistry of the product as shown below:
E2 elimination takes place in one step, therefore, dehydrohalogenation take place and result in the formation of alkene as shown above.
Ans:Draw the product formed by the reaction of potassium t-butoxide with (1S,2S)-1-bromo-2-methyl-1-phenylbutane (shown b...
Draw the product formed by the reaction of t-butoxide with (1R,2S)-1-bromo-2-methyl-1-phenylbutane (shown below). (Draw the correct stereoisomer of the product.)
Draw the product formed by the reaction of t-butoxide with (1R,2S)-1-bromo-2-methyl-1-phenylbutane (shown below). (Draw the correct stereoisomer of the product.)
Draw the product formed by the reaction of t-butoxide with (1R,2S)-1-bromo-2-methyl-1-phenylbutane (shown below). (Draw the correct stereoisomer of the product.)
Draw the product formed by the reaction of t-butoxide with (1R, 2S)-1-bromo-2-methyl-1-phenylbutane (shown below). (Draw the correct stereoisomer of the product.) 1 (CH),co“K (CH,,COH Hoc!!! H3C
Draw the product formed by the reaction of t-butoxide with (1R,2S)-1-bromo-2-methyl-1-phenylbutane (shown below). Draw the correct stereoisomer of the product. Draw the product as a skeletal structure. H, Br (CH3),coºk* (CH3),COH Hzclllll CH2 H3C/ Previous Check Answer Next Exit
Draw the product formed by the reaction of t-butoxide with (1R,2S) 1-bromo-2-methyl-1-phenylbutane (shown below). Draw the correct ste of the product. Draw the product as a skeletal structure Br (CH, Co K CH, COH H3C CH2 H3C
Draw all possible products of the reaction between NaOEt and
[(1S,2S)-1-bromo-2-methylbutyl]benzene.
2. Draw all possible products of the reaction between NaOEt and [(15,2S)-1-bromo-2-methylbutyl]benzene. Br NaOET EtOH
A) Reaction of
3-bromo-3-methylpentane and H2O and heat
Draw the major product formed when the structure shown below
undergoes substitution in H2O with heat.
B)Substitution reaction of 3-bromo-3-methylpentane and CH3OH
Draw the major product formed when the structure shown below
undergoes solvolysis in CH3OH.
1. (1R, 2R)-1-bromo-1,2-dimethylcyclohexane is heated in the presence of potassium tert-butoxide (KO-tert-Bu). Name minor product/s only 2. 2-iodo-1,1,2,3,3-pentamethylcyclohexane is heated in the presence of sodium ethoxide in ethanol, don’t name the product/s of the reaction 3. ,2,2-trimethylcyclohexan-1-ol is heated in aqueous sulfuric acid 4. (3S)-2-methyl-3-pentanol is heated in aqueous sulfuric acid
3. When 1-bromo-1-phenyl-ethane is heated in ethanolic potassium ethoxide, the major product is styrene. a. Write a detailed reaction scheme. b. Write a detailed mechanism using the standard conventions 4. When 2-bromo-1-phenylbutane is reacted in methanolic sodium methoxide, one might expect to see two products. However, only one product is formed to an appreciable extent, a. Write a detailed reaction scheme b. Write a detailed mechanism. c. Explain why only one of the possible products is formed to appreciable extent