Question

DISCUSSION QUESTION WEEK 5 NEOPLASIA A 30 y/o women has experienced heavy menstrual bleeding and is told she has a uterine tumot called a leiomyoma. She is worried she has cancer Answer the following questions related to this case study and don't forget your references 1. Explain the difference between a leiomyoma and a leiomyosarcoma. 2. How would you go about explaining the difference to her?

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Answer 1

QUESTION 1:

ANSWER:

LEIOMYOMA:

• Leiomyoma is the most common neoplasm in women and affecting the uterus.
• Leiomyoma are the benign smooth muscle tumors that occur in the uterine wall and not metastatic.
• Leiomyoma are not invasive and occur anywhere on the smooth muscle.E.X: Nipple, scrotum, labia, uterus.
• Leiomyoma are hemorrhagic / necrotic and well circumscribed.
• During treatment of leiomyoma the excision can be curable.
• In microscopic appearance the cells have low mitotic activity with blunt nuclei.
• Leiomyoma may spontaneously occur in any muscle.
• Metastatic Leiomyoma after surgery are extremely rare complication.The most common site of occurrence of leiomyoma are lungs and pelvis.

LEIOMYOSARCOMA:

• Leiomyossarcoma is a type of soft tissue sarcoma.
• Leiomyosarcoma are malignant type (cancerous).
• It has been said that leiomyosarcoma are not developed from the leiomyoma.
• Leiomyosarcoma are usually bulky, invasive masses within the uterine wall.
• Leiomyosarcoma appears to grow on the middle layer of the blood vessel that is on tunica media.
• Leiomyosarcoma has poor prognosis.
• Leiomyosarcoma and leiomyoma are quite difficult to differentiate.
• In the microscopic appearance it is hemorrhagic and necrotic tissue mets on the lung.

QUESTION:2

ANSWER:

• Leiomyoma is easily treatable and the complication from the removal of tumor is extremely rare one.
• But the leiomyosarcoma is a complicated one because it is metastatic cancer and there will be the chance for spreading to the other organs.
• It is difficult to differentiate both cancer but both are treatable.
• Post operative care is highly essential for both conditions.
• After the removal of tumor check whether the spreading is there or not.