Homework Answers
Conversion of glutamic acid to alphaketoglutarate is the anaplerotic reaction.
As anapleortic reactions are those reactions which replenish the intermediates formed in a cycle. Citric acid cycle is amphibolic which involves both catabolic as well as anabolic process. Alpha ketoglutarate served as a precursor of glutamate. So, this is one is replenished by anapleortic reaction
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Which of the following is an anaplerotic reaction for the citric acid cycle? O conversion of pyruvate to acetyl-CoA...
not sure about reaction 3 and 4 acetyl-CoA COA The reactions of the citric acid cycle...
not sure about reaction 3 and 4
acetyl-CoA COA The reactions of the citric acid cycle are shown in the figure Reactions 1, 3, and 4 are regulation points in the citric acid cycle. 1 citrate oxaloacetate 1 synthase citrate NADH + NAD malate dehydrogenase aconitase 2 malate Which of the molecules inhibits reaction 1? Isocitrate HO 17 fumarase NAD socitrate 3 dehydrogenase S D NADP ADP ОАТР O citrate synthase fumarate FADHI succinate co-ketoglutarate dehydrogenase ci-ketoglutarate NAD dehydrogenase +...
acetyl-CoA COA The reactions of the citric acid cycle are shown in the image. As labeled...
acetyl-CoA COA The reactions of the citric acid cycle are shown in the image. As labeled in the diagram, reactions 1, 3, and 4 are regulation points in the citric acid cycle. oxaloacetate citrate synthase citrate NADH +Hi 7 malate dehydrogenase NAD malate aconitase 2 Which molecule inhibits reaction 1? isocitrate 7 fumarase NAD isocitrate dehydrogenase 3 NADH + H+ O citrate O NAD acetyl-CoA + CO2 fumarate C-ketoglutarate FADH succinate O dehydrogenase FAD O-ketoglutarate a dehydrogenase NAD + COA...
Describe “hub” molecules acetyl CoA and pyruvate that serve different pathways. Explain metabolic regulation favoring metabolic pathway choices leading to and from hub molecules. Describe how C.A.C. s...
Describe “hub” molecules acetyl CoA and pyruvate that serve
different pathways. Explain metabolic regulation favoring metabolic
pathway choices leading to and from hub molecules. Describe how
C.A.C. serves as a “hub “pathway. Use picture as a reference.
Pyruvate Glucose Fatty acids sterols pyruvate carboxylase Acetyl-CoA PEP carboxykinase Glutamine Citrate Phosphoenolpyruvate (PEP) Proline Arginine Oxaloacetate PEP carboxylase Citric acid cycle a-Ketoglutarate Malate Glutamate Aspartate Asparagine Serine Glycine Cysteine malic enzyme Purines Succinyl-CoA Phenylalanine Pyrimidines Pyruvate Tyrosine Tryptophan Porphyrins heme Figure 16-16...
6. In mammals, which of the following does not occur during the citric acid cycle? A)...
6. In mammals, which of the following does not occur during the citric acid cycle? A) formation of a-ketoglutarate. D) metabolism of acetate to carbon dioxide and water. B) net synthesis of oxaloacetate from acetyl-CoA. E) oxidation of acetyl-CoA. C) generation of NADH and FADHz. 7. Which of the following reaction generates GTP(ATP) in the CAC? A) Isocitrate to a-ketoglutarate. D) Fumarate to Malate. B) Malate to Oxaloacetate. E) Succinyl-CoA to Succinate. C) a-ketoglutarate to Succinyl-CoA.
The levels of which metabolite determine whether acetyl COA can enter the citric acid cycle? a....
The levels of which metabolite determine whether acetyl COA can enter the citric acid cycle? a. succinate b. a-ketoglutarate c. citrate d. oxaloacetate
One of the early steps in the citric acid cycle is the conversion of oxaloacetate to...
One of the early steps in the
citric acid cycle is the conversion of oxaloacetate to citrate..
see picture for more details
1. One of the early steps in the citric acid cycle is the conversion of oxaloacetate to citrate (see below). Propose a mechanism for this two step process using water and acidic/basic groups on the enzyme as needed (think NAC and NAS) OOC COO S- CoA. CH H20 O -C HO O -C CH citrate synthase CH CH2...
Acetyl-CoA labeled with C, as shown, can enter the citric acid cycle. Assuming all the acetyl-CoA...
Acetyl-CoA labeled with C, as shown, can enter the citric acid cycle. Assuming all the acetyl-CoA enters the cycle... 1. What fraction of the label will be present in oxaloacetate at the end of one turn of the cycle? 14 2. Which carbons in the oxaloacetate formed by one turn of the cycle would contain the radioactive label? C4 C3 C2 Ci .What fraction of the original radiolabel present in the acetyl-CoA will be present in oxaloacetate at the end...
Part B Use the structures given in the cycle shown before this part identify the enzymes involved in each step of the citric acid cycle by completing each sentence Match the words in the left column...
Part B Use the structures given in the cycle shown before this part identify the enzymes involved in each step of the citric acid cycle by completing each sentence Match the words in the left column to the appropriate blanks in the sentences on the right. View Available Hint(s) Reset Help isocitrate dehydrogenase aconitase citrate synthase fumarate hydratase succinate dehydrogenase succinyl-CoA synthetase a-ketoglutarate dehydrogenase malate dehydrogenase In step 1, oxaloacetate condenses with acetyl-CoA to form citrate, which is catalyzed by...
37. If citric acid cycle enzymes are being inhibited, excess acetyl-CoA cannot be processed in the...
37. If citric acid cycle enzymes are being inhibited, excess acetyl-CoA cannot be processed in the citric acid cycle. This excess acetyl-CoA could be utilized to form A. pyruvate. B. oxaloacetate (OAA). C. fatty acids. A and B all of the above
_--carbon molecule QUESTION 10 During the citric acid cycle, acetyl CoA covalently binds to oxaloacetate to...
_--carbon molecule QUESTION 10 During the citric acid cycle, acetyl CoA covalently binds to oxaloacetate to form citrate, a A six B four C. five D. two E three
not sure about reaction 3 and 4
acetyl-CoA COA The reactions of the citric acid cycle are shown in the figure Reactions 1, 3, and 4 are regulation points in the citric acid cycle. 1 citrate oxaloacetate 1 synthase citrate NADH + NAD malate dehydrogenase aconitase 2 malate Which of the molecules inhibits reaction 1? Isocitrate HO 17 fumarase NAD socitrate 3 dehydrogenase S D NADP ADP ОАТР O citrate synthase fumarate FADHI succinate co-ketoglutarate dehydrogenase ci-ketoglutarate NAD dehydrogenase +...
acetyl-CoA COA The reactions of the citric acid cycle are shown in the image. As labeled in the diagram, reactions 1, 3, and 4 are regulation points in the citric acid cycle. oxaloacetate citrate synthase citrate NADH +Hi 7 malate dehydrogenase NAD malate aconitase 2 Which molecule inhibits reaction 1? isocitrate 7 fumarase NAD isocitrate dehydrogenase 3 NADH + H+ O citrate O NAD acetyl-CoA + CO2 fumarate C-ketoglutarate FADH succinate O dehydrogenase FAD O-ketoglutarate a dehydrogenase NAD + COA...
Describe “hub” molecules acetyl CoA and pyruvate that serve
different pathways. Explain metabolic regulation favoring metabolic
pathway choices leading to and from hub molecules. Describe how
C.A.C. serves as a “hub “pathway. Use picture as a reference.
Pyruvate Glucose Fatty acids sterols pyruvate carboxylase Acetyl-CoA PEP carboxykinase Glutamine Citrate Phosphoenolpyruvate (PEP) Proline Arginine Oxaloacetate PEP carboxylase Citric acid cycle a-Ketoglutarate Malate Glutamate Aspartate Asparagine Serine Glycine Cysteine malic enzyme Purines Succinyl-CoA Phenylalanine Pyrimidines Pyruvate Tyrosine Tryptophan Porphyrins heme Figure 16-16...
6. In mammals, which of the following does not occur during the citric acid cycle? A) formation of a-ketoglutarate. D) metabolism of acetate to carbon dioxide and water. B) net synthesis of oxaloacetate from acetyl-CoA. E) oxidation of acetyl-CoA. C) generation of NADH and FADHz. 7. Which of the following reaction generates GTP(ATP) in the CAC? A) Isocitrate to a-ketoglutarate. D) Fumarate to Malate. B) Malate to Oxaloacetate. E) Succinyl-CoA to Succinate. C) a-ketoglutarate to Succinyl-CoA.
One of the early steps in the
citric acid cycle is the conversion of oxaloacetate to citrate..
see picture for more details
1. One of the early steps in the citric acid cycle is the conversion of oxaloacetate to citrate (see below). Propose a mechanism for this two step process using water and acidic/basic groups on the enzyme as needed (think NAC and NAS) OOC COO S- CoA. CH H20 O -C HO O -C CH citrate synthase CH CH2...
Acetyl-CoA labeled with C, as shown, can enter the citric acid cycle. Assuming all the acetyl-CoA enters the cycle... 1. What fraction of the label will be present in oxaloacetate at the end of one turn of the cycle? 14 2. Which carbons in the oxaloacetate formed by one turn of the cycle would contain the radioactive label? C4 C3 C2 Ci .What fraction of the original radiolabel present in the acetyl-CoA will be present in oxaloacetate at the end...
Part B Use the structures given in the cycle shown before this part identify the enzymes involved in each step of the citric acid cycle by completing each sentence Match the words in the left column to the appropriate blanks in the sentences on the right. View Available Hint(s) Reset Help isocitrate dehydrogenase aconitase citrate synthase fumarate hydratase succinate dehydrogenase succinyl-CoA synthetase a-ketoglutarate dehydrogenase malate dehydrogenase In step 1, oxaloacetate condenses with acetyl-CoA to form citrate, which is catalyzed by...
_--carbon molecule QUESTION 10 During the citric acid cycle, acetyl CoA covalently binds to oxaloacetate to form citrate, a A six B four C. five D. two E three
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