Question

a. Using the table below, predict the secondary structure most likely adopted by the heptapeptide "RANGEHEAL". Will it be alpha-helical, beta-strand, or just random coil?
Conformational Preferences of the Amino Acids Preference Amino acid a-helix B-strand Reverse turn Glu 1.59 0.52 1.01 Ala 1.41

b. Hydrogen bonds between backbone residues stabilize interactions between ​\alpha helixes and ​\beta sheets. Knowing this and other information about hydrogen bonds, which amino acid from the picture below will destabilize secondary protein structure?
A K, (H2C)4 NH3 F P N. D H Nww. IZ LL

Conformational Preferences of the Amino Acids Preference Amino acid a-helix B-strand Reverse turn Glu 1.59 0.52 1.01 Ala 1.41 0.72 0.82 Leu 1.34 1.22 0.57 Met 1.30 1.14 0.52 Gln 1.27 0.98 0.84 Lys 1.23 0.69 1.07 Arg 1.21 0.84 0.90 His 0.80 1.05 0.81 Val 0.90 1.87 0.41 lle 1.09 1.67 0.47 Tyr 0.74 1.45 0.76 Cys 0.66 1.40 0.54 Trp 1.02 1.35 0.65 Phe 1.16 1.33 0.59 Thr 0.76 1.17 0.90 Gly 0.43 0.58 1.77 Asn 0.76 0.48 1.34 Pro 0.31 0.34 1.32 Ser 0.57 0.96 1.22 Asp 0.99 0.39 1.24


A K, (H2C)4 NH3 F P N. D H Nww. IZ LL
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Answer #1

Awst Avwino aud Thre letlex code Prelerene od- helix -helix Angiaine CA-g) (Ala) 1.) R 2AAlnine 3) N Tevexse furm Sevee lumn

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