Predict the products for the following reactions. Note – think about the base being used – is it catalytic? If so, can the product molecule ring-close?
Predict the products for the following reactions. Note – think about the base being used – is it catalytic? If so, can t...
4. Draw the products of the following sequences of reactions. 1) NaOET, HOE 1) NaOEt Eto OEt 2) H3O+ 2) Br | 1) LDA, -78°C 2) 0 H30+ heat H 3) NaOH, heat 1) LDA (1.1 equiv), -78°C, THE 2) CH3Br 1) CH3CH2MgBr 2) H30* H2, Pd-C LU H2SO4 NaOH, H2O 1) LDA, -78°C 2) HOE 3) H30+ 1) O3 2) CH2SCH3
Predict the appropriate structure for I - V. 1 1. Predict the appropriate structure for I-V. 1. NaOEt 3. NaOH II 5. (0) LDA, -78 °C Eto 2. EtBr III 4. H30* / heat (ii) benzaldehyde 6. H30+ / heat 7. Et Culi V IV 8. Mel
.Predict the appropriate structure for I-V. 1. Predict the appropriate structure for I-V. 1. NaOEt 3. NaOH II 5. (0) LDA, -78 °C Eto 2. EtBr III 4. H30* / heat (ii) benzaldehyde 6. H30+ / heat 7. Et Culi V IV 8. Mel
give mechanism 3.1 sc)o 2. CH3(CH)&B \ 3. Нзо", heat O/ d) 1. NaOEt 2. dil. H3O OEt 1. LDA, -78°C 2. CH CH2Br f) 1. NaOH, 2 2. H30 1. NaOH, heat g) xs NH3 (SN2) 1. Br2, PBr3 2. H20 h)
? What set of reactions are necessary to carry out the following transformation? Ph 1. Brz, NaOH, then Ht workup 2. Pyridine, Heat 3. Ph Culi, then H20 workup 1. Brz, Acetic acid 2. Pyridine, Heat 3. Ph Culi, then H20 workup A B 1. Brz, NaOH, then Hworkup 2. Phli, then H20 workup 1. PhMgBr, then H20 workup 2. Brz. NaOH, then H* workup 3. Pyridine, Heat C D Zoom A A B B С D D E More...
Provide the major product(s) for the following Provide the major product(s) for the following reactions. Be sure to note stereochemistry and racemic mixtures. NaOH, H29 2 100 °Ç ? NaOH, H2O H 0°C H W H CCl3 OC (provide product of both steps) H a. Hn b. CHEM 370 W13 Homework Page 1 of 2 giorel Noot Hoi solu NOEL IN DER NaOH, H2O 100 °C Hv NaOET, H OEt EtOH 8. Eto- i. LDA, -78°C NaO Me MeOH Оме...
1) The reaction below proceeds via a multistep mechanism involving several intermediate structures en route to the final product. Some possible structures for the intermediates and product have been provided below. Decide which intermediates are involved in the reaction, and what the final product is, and place them in the correct order (e.g. A +B+C where C would be the final product isolated). (4 points) 1) NaOET, Eto OEt 2) NHACI, H20 Possible intermediates/products: Eto OET Eto OET Eto OET...
please write the step by step proudct of the foloewing sequence of reactions 1. Catalytic NaOEt/EtOH 2. H2O', heat 3. (CH2CH2),Culi 4. Mild H2o+ 5.1.0 Equiv. LDA Η An aldehyde 7. Mild H2o+
le chatelier experimen Thursday). 1. What starting material and reagents are needed for the following multi-step synthesis (HINT: aldol reactions work best when the starting material can only form one enolate)? 5 он о D. NaOH, H2O, Heat F. HO E. NaOH, H2O G. LDA Starting Material: Reagents: 2. LDA is a strong, sterically hindered base and will form the enolate. Sodium hydride is a weak base and will form the _ - enolate. Kinetic enolates are the stable and...
Hi I need help predicting the products for these reactions OEt NaOCH.CH CH,CH OH b. H, O/H,0 a. NaOCH.CH CH,CH,OH b. Br c. NaOHH O, beat d. H2O*/H2O 1. NaCN, DMSO 2. CH,MgBr, Eto 3. H.O/H,O EN 2. NaH, CH,Br chemoselective 1. a. NaOet, EtOH Br b. 2. a. NaOH/H,O, heat b. H30+/H20 CY.NECEN cy OH b. then add HC-NH2 a. NaCN, DMSO b. HO*/H,0