Question

A patient, suffering from malnutrition needs to start parenteral supplement having the following composition.

Sodium chloride 54 mEq/L

Potassium phosphate 105 mEq/L

Potassium chloride 20 mEq/L

Magnesium sulfate 10 mEq/L

Calcium gluconate 9.6 mEq/L

Sodium acetate 70 mEq/L

As a hospital pharmacist you received the medication order for 2.5 liters of this supplement. Calculate the following parameters.

1) Amount of each ingredient in grams in the whole prep

2) Molarity of each ingredient in the preparation in mmole/L

3) Osmolarity of each ingredient & the whole preparation

Answer 1

0 Amount of each ingredient in grams in the whole prep Given composition, Sodium chloride (Nad) = 54 meglL Pottassium chloride (Ked) = m Egl/L Pot tassium phosphate (K₃ PO 4) = 105 mEq/L Magnesium sultate (My soy) = 10 m Egl L alcium gluconate (C1242 290, 4) = 9.6mEq/L sodium Acetate (CH₂COo Na)= 70 m Eg IL erton per liter factor No. of mEquivalents = No. of milli moles x Per Liter No. of milli moles = No. of m. tq les L per t h -factor I - Per L No. of millimoles of Nad= n-factor 54 of Nad = 1) No. of milli moles of k d = 20 in-factor of Kd = 1) Per L No. of millimoles of K₂ Poy = 105 [:n-factor = 3 No-ot millimoles of My sou = 10 [in-tactor=2] Pert No. of millimeles of C., 2 M 2 Q Q q = 9.6 [n-factor=2] No. of millimoles of CHCOONa = 70 [.n-tactor= 1 weight an ma- No. of millimoles y Per L 3 Pes L Molar • Mass Pen L - Pes L

Weight of Nad in mg = 544 58-5 = 3,159 74-5 weight of kd in mg = 80% Bale = 1,490 Pen L o n Weight of K₂ poy in mg = 35x 167 = 5,845 ker L weight of magson in mg = 5 x 120 = 600 weight of C2 H22 Ca Oly in mg_4.8 x 430 = 2,064 Per L Per L Weight of CH₃COONa in mg = 70x82 = 5,740 Pes Le weight of Nad in g per L = 3-159 g weight of kd in g per L = 1- 490g weight of K₃PO4 in g per L = 5.8459 weight of Masou in g per L = 0.6 g weight of C, 2 h 22 CG 0,4 in a pea L = 2-0649 weight of CH₂ COONa in g per L = 5-74g. Total ingredient in q per L= 18-898 g Total weight of ingredients ing per 2.5L = 18-2 =47-2459